| 孙伟楠 刘冰熔△ 刘中宏 金世柱 刘丹.胃镜对咽喉部恶性病变诊断的临床应用价值[J].现代生物医学进展英文版,2016,16(11):2074-2077. |
| 胃镜对咽喉部恶性病变诊断的临床应用价值 |
| The Clinical Application Value of Gastroscopy in the Diagnosis of Pharynxand Laryngeal Malignant Lesions |
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| DOI： |
| 中文关键词: NBI放大胃镜 咽肿瘤 喉肿瘤 |
| 英文关键词: NBI magnifying gastroscopy Pharyngeal neoplasms Laryngeal neoplasms |
| 基金项目:国家自然科学基金项目（30871152） |
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| 中文摘要: |
| 目的：探讨胃镜在对于咽喉部恶性疾病诊断的临床应用价值。方法：对2013 年11 月至2014 年9 月因声音嘶哑或咽部异物
感或吞咽困难为主诉就诊的患者，给予电子喉镜或间接喉镜检查，以在喉镜下发现咽喉部肿物或喉镜下发现黏膜异常增生不能
明确判定病灶性质的12 例患者为研究对象。继而给予窄带成像（Narrow-band imaging，NBI）及放大胃镜检查，对病灶进行性质及
病变范围的判定。病理结果作为金标准，比较喉镜及胃镜两种方式对咽喉恶性病灶的正确诊断率。结果：12例患者中共发现15 处
病灶，其中炎性反应5 处，单纯性鳞状上皮增生3 处，鳞状细胞癌6 处，神经纤维瘤1 处。喉镜对病灶的正确诊断率是40.0 %
（6/15），NBI放大胃镜对病灶的正确诊断率是93.3 %(14/15)，两者差异有统计学意义（x2=9.60，P=0.005）。结论：NBI放大胃镜对咽
喉部肿瘤诊断正确率高于普通喉镜，充分证明了胃镜在咽喉部恶性疾病的诊断方面的临床价值。在行胃镜检查时，同时对咽喉部
进行仔细观察检查是十分必要的。 |
| 英文摘要: |
| Objective:To investigate the clinical value of Gastroscopy in the diagnosis of pharynx and laryngeal malignant lesions.Methods:This study collected the patients from 2013 November to 2014 September in our because of hoarseness or pharyngeal foreign
body sensation or with chief complaint of dysphagia, and gave themthe examination by electronic laryngoscope or indirect laryngoscopy,
we regarded the patients who found out the throat tumor or the dysplasia found by laryngoscope which could not determine the nature of
the lesions as our target, about 12 cases of patients were regarded as the research objects in this study. Then we gave these patients gastroscopy
and narrow band imaging (NBI) magnifying endoscopy examination to determine the nature and extent of the lesions. We regarded
the pathological results as the gold standard of diagnosis, compared the diagnostic accuracy of laryngoscope and NBI magnifying
endoscopy.Results:Among the 12 patients, a total of 15 were detected by laryngoscope and gastroscopy. The histological diagnoses of
these lesions were as follows: 5 inflammatory, 3 simple hyperplasia of squamous epithelium, 6 squamous cell carcinoma, 1 schwannoma.
The diagnostic accuracy by laryngoscope of these lesions was 40.0 %(6/15), which was lower than that of NBI magnifying gastroscopy
93.3% (14/15), x2=9.60, P=0.005.Conclusion:NBI magnifying gastroscopy has higher diagnostic accuracy than laryngoscope in diagnosis
of laryngopharyngeal carcinoma. It fully proved the clinical value of gastroscopy in the diagnosis of laryngopharyngeal diseases.
When we give the patient gastroscopy, observation of the pharynx and laryngeal is necessary. |
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