| 肖瑶 石赟 刘彦 张净 张健△.社区获得性肺炎并发革兰阴性菌感染的病原菌分布及危险因素分析[J].现代生物医学进展英文版,2016,16(8):1498-1501. |
| 社区获得性肺炎并发革兰阴性菌感染的病原菌分布及危险因素分析 |
| Analysis of Pathogenic Bacteria Distribution and Risk Factors in CommunityAcquired Pneumonia Complicated by GramNegative Bacteria Infection |
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| DOI： |
| 中文关键词: 社区获得性肺炎 革兰阴性菌 病原菌 分布 危险因素 |
| 英文关键词: Community acquired pneumonia Gramnegative bacteria Pathogenic bacteria Distribution Risk factors |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨社区获得性肺炎（CAP）并发革兰阴性菌感染的病原菌分布及危险因素，以降低感染率。方法：选择2013年6 月到
2015 年6月我院确诊CAP 患者80 例，收集所有患者的临床资料，分析CAP并发革兰阴性菌感染的病原菌分布及危险因素。结
果：CAP并发革兰阴性菌感染的病原菌以肺炎克雷伯菌株数最多，13 株（占30.23%），其次为大肠埃希菌8 株（占18.60%）和鲍曼
不动杆菌7 株（占16.28%）。感染阳性组入院治疗前使用抗生素、白细胞水平异常、PORT≥ 3 级以及血尿素氮水平＞7.1 mmol/L
的比例较感染阴性组显著更高，差异均有统计学意义（均P＜0.05）。由Logistic 回归分析可知，入院治疗前使用抗生素、白细胞水
平异常、PORT≥ 3 级以及血尿素氮水平＞7.1 mmol/L均为影响CAP患者发生革兰阴性菌感染的危险因素。结论：CAP并发革兰
阴性菌感染的病原菌主要以肺炎克雷伯菌，大肠埃希菌和鲍曼不动杆菌为主，临床上应重视CAP并发革兰阴性菌感染危险因素，
以降低感染率。 |
| 英文摘要: |
| Objective:To discuss pathogenic bacteria distribution and risk factors in community acquired pneumonia complicated
with infection of gram negative bacteria, and to reduce the infection rate.Methods:Chose 80 patients with CAP who were diagnosed as
CAP in our hospital from June 2013 to June 2015, collected the clinical data of CAP patients.The clinical characteristics and risk factors
of gram negative bacterial infection were analyzed.Results:CAP complicated with infection of gram negative bacteria with
trees was the most, 13 strains (accounted for 30.23%), followed by 8 strains of (accounted for 18.6%) and 7
strains of Bormann real coli (accounted for 16.28%). Infection positive group's the use of antibiotics before hospitalized, abnormal levels
of white blood cells, PORT≥ 3 and level of blood urea nitrogen>7.1 mmol/L proportion were significantly higher, the differences were
statistically significant (P<0.05). With logistic regression analysis showed the use of antibiotics before hospitalized, abnormal levels of
white blood cells, PORT≥ 3 and level of blood urea nitrogen>7.1 mmol/L was gram negative bacteria infection risk factors.Conclusion:The pathogenic bacteria of CAP complicated by Gramnegative bacteria infection in patients is mainly caused by ,
and . The main clinical treatment should pay attention to the risk factors of infection caused by CAP infection,
so as to reduce the infection rate. |
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