| 张莉莉 高阳 丁建 经子兰 马颖艳.不同性别急性心梗患者的临床特征及院内治疗预后分析[J].现代生物医学进展英文版,2016,16(7):1299-1302. |
| 不同性别急性心梗患者的临床特征及院内治疗预后分析 |
| Clinical Features, Treatments and Short-termOutcome of Male and FemalePatients with Initial Acute Myocardial Infarction |
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| DOI： |
| 中文关键词: 性别 急性心肌梗死 临床特征 治疗 短期预后 |
| 英文关键词: Gender Acute myocardial infarction Clinical feature Treatment Short-termoutcome |
| 基金项目:国家科技支撑计划项目（2011BAI11B00）；军队临床高新技术重大项目（2010gxjs001） |
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| 中文摘要: |
| 目的：观察首次确诊为急性心肌梗死（AMI）患者的临床特征并分析不同性别人群的在入院治疗及院内短期预后的差异。方
法：回顾性分析2010 年2 月至2012 年4 月在沈阳军区总医院心内科初次确诊为AMI的患者271 例，并按性别分为两组，其中男
性组180 例，女性组91 例，统计其临床特征、入院后的药物和手术治疗情况，以及院内并发症及预后情况，分析总结两组患者各
自的特点和差异。结果：女性患者的年龄要大于男性患者（63± 14vs71± 11，P＜0.001），且同时更易患有高血压等心血管疾病合并
症（73.3%vs 58.2%，P＜0.05）。女性患者的发病至入院治疗时间长于男性（P＜0.001），且入院后行PCI治疗的比例要明显低于男
性患者（67% vs 79.4%，P＜0.05）。初步分析结果表明，女性患者的院内死亡率高于男性（11% vs 3.3%，OR：3.11，95%CI：
1.53-7.15），但排除不均衡因素的影响后，男女患者的院内死亡率无明显差异（OR：2.11，95%CI：0.68-5.12）。结论：两性AMI 患者
的临床特征、入院后治疗及院内短期预后均存在一定差异。根据女性患者的临床特征和院内治疗及预后的现状，应进一步加强对
女性高危人群的冠心病诊治知识普及和教育，且对入院后的女性患者应采取更为积极的药物和介入手术治疗手段，以改善预后。 |
| 英文摘要: |
| Objective:To evaluate the gender differences in clinical features, hospital treatments, in-hospital complications and
outcomes of patients with an initial acute myocardial infarction (AMI).Methods:Retrospective analysis was carried out in 271 patients
with initial AMI, including 180 male and 91 female. The clinical data of clinical features, hospital treatment, in-hospital complications
and outcome were then compared between the two groups.Results:The female patients were older (63± 14 vs 71± 11, P<0.001) and
were more likely than the male patients to have had previously diagnosed comorbidities, such as hypertension (73.3%vs 58.2%, P<0.05).
And the female patients were more likely to have delayed seeking medical care after the onset of AMI than male patients (P<0.001). In
addition, during hospitalization, female were less likely to have undergone percutaneous coronary intervention (PCI) compared with male
(67%vs 79.4 %, P<0.05). The results of preliminary analysis indicated that female patients experienced higher in-hospital mortality than
male (11 % vs 3.3 %, OR：3.11, 95 %CI: 1.53-7.15). However, the differences were decreased after adjustment for imbalance factors
(OR: 2.11, 95 %CI: 0.68-5.12).Conclusion:The clinical features, hospital treatments, in-hospital complications and outcomes were different
between male and female patients with initial AMI. The targeted and timely healthy education for female high-risk population of
coronary heart disease should be further strengthened. And more aggressive treatments for female AMI patients should be taken to improve
the prognosis. |
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