| 孙雷雷 杜英杰 车淑玉 邱宽 林楠 周长勇.IABP支持下急诊PCI治疗急性心肌梗死并心源性休克的疗效观察[J].现代生物医学进展英文版,2016,16(6):1111-1114. |
| IABP支持下急诊PCI治疗急性心肌梗死并心源性休克的疗效观察 |
| Therapeutic Effect of Emergency Percutaneous Coronary InterventionAccessory Intra-aortic Balloon Pump in Patients with Acute MyocardialInfarction Combined with Cardiogenic Shock |
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| DOI： |
| 中文关键词: 急性心肌梗死 心源性休克 主动脉内球囊反搏 经皮冠状动脉介入治疗 |
| 英文关键词: Acute myocardial infarction Cardiogenic shock Intra-aotic balloon counterpulsation Percutaneous coronary
intervention |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨主动脉内球囊反搏（IABP）支持下急诊经皮冠状动脉介入(PCI)治疗急性心肌梗死（AMI）并心源性休克（CS）的临
床疗效。方法：选取急诊PCI治疗的AMI并CS的患者47 例，24 例接受IABP支持下急诊PCI治疗的患者为治疗组，23例直接急
诊PCI治疗的患者为对照组。治疗一周后，检测两组患者平均动脉压（MAP）、尿量、心率、肺动脉楔压（PCWP）、心脏指数（CI）、左
室射血分数（LVEF）、及N 末端血浆B 型尿钠肽前体（NT-proBNP）指标的变化，多巴胺、速尿和硝酸酯类用量的比较及死亡率比
较。结果：治疗前两组各项观察指标差异无统计学意义（P＞0.05）；治疗后两组各项观察指标与治疗前比较，差异均有统计学意义
（P＜0.05）；治疗后两组各观察指标差值比较，差异有统计学意义（P＜ 0.05）；治疗组多巴胺、速尿用量少于对照组，差异有统计学
意义（P＜0.05）；治疗组硝酸酯类用量少于对照组，但差异无统计学意义（P＞ 0.05）；治疗后两组死亡率比较，差异有统计学意义
（P＜0.05）。结论：急性心肌梗死并心源性休克患者在IABP 支持下行急诊PCI，可明显改善患者的冠状动脉血流，改善心肌的血
供，改善心功能，降低病死率。 |
| 英文摘要: |
| Objective:To evaluate the therapeutic effect of emergency percutaneous coronary intervention accessory intra-aortic
balloon pump in patients with acute myocardial infarction combined with cardiogenic shock.Methods:Clinical data of AMI combined
with cardiogenic shock from 47 patients were collected. Twenty-four cases of treatment group were performed with emergency PCI with
accessory IABP, and twenty-three cases of control group were performed with emergency PCI. One week ago, the mean arterial pressure
(MAP), urine volume, heart rate, pulmonary capillary wedge pressure(PCWP), cardiac index(CI), left ventricular ejection fraction(LVEF),
NT-proBNP was observed and compared between the two groups. The dosage of dopamine, furosemidum and Nitrates and the mortality
was compared between two groups.Results:Before the treatment, the items of two groups had no significantly differences (P＞0.05); the
items of two groups both had significantly differences after the treatment compared with before treatment (P＜0.05); after the treatment,
the differentials of the items of the two groups had significantly differences (P＜0.05). The dosage of dopamine and furosemidum was
lower in the treatment group than that of the control group, and had significantly differences (P＜0.05); the dosage of Nitrates was lower
in the treatment group than that of the control group, but had no significantly difference (P＞0.05). The mortality of two groups had
significantly differences (P＜0.05).Conclusion:The emergency PCI with accessory IABP therapy in the patients with acute myocardial
infarction combined with cardiogenic shock can significantly increase coronary perfusion and improve myocardial blood supply, thereby
improve cardiac function, reduce the mortality. |
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