| 陈漫天 汪志泉 舒红 沈成兴 施维捷.碘克沙醇对介入后ST段抬高性心肌梗死的有效性及安全性[J].现代生物医学进展英文版,2016,16(6):1054-1057. |
| 碘克沙醇对介入后ST段抬高性心肌梗死的有效性及安全性 |
| Effect of Iodixanol Injection in Treatment of Patients with ST SegmentElevation Myocardial Infarction |
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| DOI： |
| 中文关键词: 碘克沙醇 ST 段抬高 心肌梗死 安全性 |
| 英文关键词: Iodixanol ST elevation Myocardial infarction Safety |
| 基金项目:上海市医学重点专科建设项目（A类）（ZK2012A04) |
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| 中文摘要: |
| 目的：探讨碘克沙醇注射液对介入治疗ST 段抬高性心肌梗死患者治疗的有效性及安全性。方法：选取我院收治的介入ST
段抬高性心肌梗死患者68 例，根据选用的造影剂的不同，分为两组，每组各34 例，其中对照组予碘普罗胺注射液，实验组予碘克
沙醇注射液。治疗后，观察并比较两组患者的影像学质量，围手术期的不良反应，术前术后的肾功能情况。结果：治疗后，与对照组
相比较，实验组的影像学质量明显改善(P＜0.05)，围手术期不良反应显著减少(P＜0.05)，肾功能改变不明显(P＜0.05)，差异均有统
计学意义。结论：碘克沙醇注射液对介入ST 段抬高性心肌梗死患者治疗造影效果好，对患者的肾功能影响较低，更为安全有效，
值得临床推广使用。 |
| 英文摘要: |
| Objective:To investigate the effect of Iodixanol injection in treatment of patients with ST segment elevation
myocardial infarction.Methods:68 patients with ST segment elevation myocardial infarction fromour hospital were selected and divided
into the control group of 34 cases and the experimental group of 34 cases by different contrast agent. The control group were treated with
Iodine and amine injection and the experiment group were treated with Iodixanol injection. The imaging quality, adverse reactions and
renal function after operation were observed and compared between two groups.Results:Compared with the control group after
treatment, the image quality in the experimental group were better (P＜0.05), and the adverse reactions during perioperative period were
also less (P＜0.05), and the renal function changes were not obvious (P＜0.05).Conclusion:Iodixanol injection has good curative effect
in intervention treatment for ST segment elevation myocardial infarction, and less impact on renal function of patients, so it is more safe
and effective, worthy of clinical use. |
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