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樊秦娥 吴立兵△ 刘雪琴 王会敏 厉梅.妊娠高血压患者血清瘦素、Cys C及beta-HCG水平检测的临床意义[J].现代生物医学进展英文版,2016,16(5):910-912.
妊娠高血压患者血清瘦素、Cys C及beta-HCG水平检测的临床意义
Clinical Significance of Detection of Leptin, Cys C and beta-HCG Levels inSerum of Patients with Pregnancy-Induced Hypertension
  
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中文关键词: 妊娠高血压  瘦素  胱抑素C  人绒毛膜促性腺激素
英文关键词: Gestational hypertension  Leptin  Cystatin C  Human chorionic gonadotropin
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Author NameAffiliation
樊秦娥 吴立兵△ 刘雪琴 王会敏 厉梅 湖北医药学院附属十堰市太和医院产科 
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中文摘要:
      目的:研究妊娠高血压患者血清瘦素、胱抑素C(CysC)以及人绒毛膜促性腺激素(beta-HCG)水平检测的临床意义。方法:选取 2014 年4 月到2015 年4月我院收治的妊娠高血压患者90 例(妊娠高血压组),另选同期正常妊娠者90 例(正常妊娠组),健康体 检非妊娠妇女90 例(对照组),测量三组血清瘦素、CysC 以及beta-HCG水平,并分析各指标的相关性。结果:妊娠高血压组和正常妊 娠组血清瘦素、CysC 以及beta-HCG水平均显著高于对照组,比较差异具有统计学意义(P<0.05),妊娠高血压组血清瘦素、CysC 以 及beta-HCG 水平均显著高于正常妊娠组,比较差异具有统计学意义(P<0.05);妊娠高血压越严重血清瘦素、CysC 以及beta-HCG 水 平越高;妊娠高血压患者血清瘦素与CysC 和beta-HCG 均呈正相关关系(P<0.05),CysC 与beta-HCG也呈正相关关系(P<0.05)。结 论:检测血清中瘦素、CysC 和beta-HCG 水平有利于妊娠高血压的诊断,体检时发现上述物质异常升高要高度重视。
英文摘要:
      Objective:To study the clinical significance of detection of leptin, Cystatin C(Cys C) and human chorionic gonadotropin (beta-HCG) levels in the serum of patients with pregnancy-induced hypertension.Methods:A total of 90 patients with pregnancy-induced hypertension, who were admitted to Shiyan Maternal and Child Health-Care Hospital of Hubei Province from April 2014 to April 2015, were chosen as pregnancy-induced hypertension group, 90 women with normal pregnancy in the same period, normal pregnancy group, 90 healthy non-pregnant women, control group. Leptin, CysC and beta-HCG levels of the three groups were detected, and the correlation among the indexes were analyzed.Results:Leptin, CysC and 茁-HCG levels in the pregnancy-induced hypertension group and normal pregnancy group were significantly higher than those in the control group, the differences were statistically significant (P<0.05); leptin, CysC and beta-HCG levels in the pregnancy-induced hypertension group were significantly higher than those in the normal pregnancy, the differences were statistically significant (P<0.05). The more serious pregnancy-induced hypertension was, the higher the levels of serum leptin, CysC and beta-HCG were; Leptin and Cys C, beta-HCG of pregnancy-induced hypertension patients had a positive correlation (P<0.05); Cys C and beta-HCG also showed a positive correlation (P<0.05).Conclusion:Detecting serum leptin, CysC and beta-HCG levels is in favour of the diagnosis of patients with pregnancy-induced hypertension.
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