| 张国强 鲁世保 杨林 王宇 梁得华.椎间植骨粒体积对腰椎滑脱融合内固定术融合效果的影响[J].现代生物医学进展英文版,2016,16(5):872-875. |
| 椎间植骨粒体积对腰椎滑脱融合内固定术融合效果的影响 |
| Effect of Bone Graft Volume on Intervertebral Fusion Fixation in theSpondylolisthesis |
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| DOI： |
| 中文关键词: 腰椎滑脱症 椎间植骨融合术 植骨粒体积 |
| 英文关键词: Spondylolisthesis Intervertebral bone fusion Bone graft volume |
| 基金项目:北京市科学技术委员会资助项目（D13110700490000） |
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| 中文摘要: |
| 目的：探讨在腰椎后路植骨融合手术中，椎间植骨粒的体积对手术效果的影响。方法：回顾性分析我院2012 年5 月-2013 年
9 月采用腰椎后路植骨融合术的75例患者的临床资料，根据患者手术中椎间植骨粒体积不同分为A 组（小体积组，5 粒/cm3）、B
组（中体积组，11粒/cm3）以及C 组（大体积组，23 粒/cm3）。分析三组患者的植骨粒体积、植骨融合率以及手术效果。结果：三组患
者植骨粒体积比较，差异具有统计学意义（P<0.05）；椎间植骨总体积比较，差异无统计学意义（P>0.05）。与术前比较，三组术后
ODI指数及VAS 评分明显下降，差异具有统计学意义（P<0.05）；但三组间比较，差异无统计学意义（P>0.05）。B 组植骨融合率高
于A 组及C 组，而A 组高于C 组，组间比较，差异均具有统计学意义（P<0.05）。手术后各组椎体滑脱程度与术前相比得到明显改
善（P<0.05）。结论：腰椎滑脱内固定术中应用中等体积植骨粒可明显提高椎体间融合率。 |
| 英文摘要: |
| Objective:To explore the effects of the bone graft volume of grain interbody on the spondylolisthesis.Methods:75 patients
with spondylolisthesis from May 2012 to September 2013 were selected and according to the different volumes of bone graft, the
patients were divided into group A (small volume, 5/cm3), group B (moderate volume, 11/cm3) and group C (large volume, 23/cm3). Then
the clinical data including volume, fusion rate, clinical results in patients with bone particles surgery in the three groups were analyzed.Results:The difference of bone graft volume was statistically significant difference among three groups (P<0.05). The volume of intervertebral
bone graft was no statistically significant among three groups (P>0.05). Compared with before operation, postoperative ODI index
and VAS score was decreased obviously in three groups with statistically significant difference (P<0.05); but there was no statistically
significant difference among three groups (P>0.05). The fusion rate of bone graft was higher in group B than group A and group C, and it
was higher in group A than that of group C, and the differences were statistically significant among groups (P<0.05). The degree of vertebral
body slippage after surgery was improved significantly than before operation (P<0.05).Conclusion:In the internal fixation of
spondylolisthesis surgery, the application of medium-volume bone graft can significantly improve the fusion rate. |
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