| 王晓红 宋涛 汪瑞人 肖铮铮 侯晓利.清开灵注射液联合阿奇霉素对支原体肺炎患儿血清T-IgE和ECP水平的影响[J].现代生物医学进展英文版,2016,16(4):717-719. |
| 清开灵注射液联合阿奇霉素对支原体肺炎患儿血清T-IgE和ECP水平的影响 |
| A Study on the Effect of Qingkailing Injection Combined with Azithromycinon T-IgE and ECP Levels in Children with Mycoplasma Pneumonia |
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| DOI： |
| 中文关键词: 清开灵注射液 阿奇霉素 小儿支原体肺炎 血清总免疫球蛋白E 血清嗜酸粒细胞阳离子蛋白 |
| 英文关键词: Qingkailing Azithromycin Mycoplasma pneumonia T-IgE ECP |
| 基金项目:辽宁省自然科学基金项目(20022074) |
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| 中文摘要: |
| 目的：探讨清开灵注射液联合阿奇霉素对小儿支原体肺炎患者血清T-IgE 和ECP影响。方法：选取我院收治的支原体肺炎
患儿50 例，随机分为实验组和对照组。两组均予阿奇霉素对症治疗，实验组在此基础上加用清开灵注射液治疗。观察并比较两组
患儿治疗前后血常规各指标变化情况以及T-IgE、ECP 水平的变化。结果：与治疗前相比，两组患者治疗后中性粒细胞比例降低，
淋巴细胞比例升高，单核细胞比例降低(P＜0.05)，且实验组治疗组中性粒细胞比例较对照组更低，淋巴细胞比例较高，单核细胞比
例较低(P＜0.05)。治疗后3、7、14 天，两组患儿的血清T-IgE 及ECP水平呈下降趋势，与前一时间点比较，两组患者的T-IgE 及
ECP 水平均较低(P＜0.05)，与对照组比较，实验组同意时间点T-IgE 及ECP水平较低(P＜0.05)。结论：清开灵注射液联合阿奇霉
素能够明显降低小儿支原体肺炎患儿血清T-IgE 和ECP 水平。 |
| 英文摘要: |
| Objective:To investigate the effect of Qingkailing Injection combined with azithromycin on T-IgE and ECP levels in
children with mycoplasma pneumonia.Methods:50 cases with mycoplasma pneumonia were randomly divided into the experimental and
control groups. Patients were treated with azithromycin and the experimental group was also treated with Qingkailing Injection. The
serum levels of T-IgE and ECP were compared before treatment and 3 days, 7 days and 14 days after the treatment.Results:Compared
with before treatment, the proportion of neutrophils decreased in both groups, lymphocytes ratio increased, the proportion of mononuclear
cells decreased after treatment (P<0.05). Compared with the control group, the proportion of neutrophils in the experimental group was
lower, the proportion of lymphocytes was higher, and the proportion of monocytes was lower after treatment(P<0.05). The levels of T-IgE
and ECP in serum decreased on 3rd, 7th and 14th day after treatment, compared with the previous time, the levels of ECP and T-IgE in
both groups were lower (P<0.05), Compared with the control group, the T-IgE and ECP levels of experimental group were lower(P<0.
05).Conclusion:Qingkailing injection combined with azithromycin could significantly decrease the serum T-IgE and ECP levels in
children with mycoplasma pneumonia. |
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