施凌云 季黎明 何华平 王磊 郭志勇.终末期肾脏病患者行维持性血液透析的营养状况及影响因素分析[J].现代生物医学进展英文版,2016,16(3):478-480. |
终末期肾脏病患者行维持性血液透析的营养状况及影响因素分析 |
Nutritional Status of Patients with End-stage Renal Disease and UnderwentMaintenance Hemodialysis and Its Risk Factors |
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DOI: |
中文关键词: 终末期肾脏病 维持性血液透析 营养不良 危险因素 |
英文关键词: End-stage renal disease Maintenance hemodialysis Malnutrition Risk factors |
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中文摘要: |
目的:探究并分析终末期肾脏病患者行维持性血液透析的营养状况及影响因素。方法:选取2010 年1 月-2014 年1 月在我
院接受维持性血液透析治疗的82 例终末期肾脏病患者,根据改良的定量主观整体评估表(MQSGA)评分将患者分为营养不良组
(>10 分)以及营养正常组,比较两组患者年龄、性别、透析时间、身体质量指数(BMI)、血红蛋白(Hb)、血尿素氮(BUN)、甘油三酯
(TG)、超敏C 反应蛋白(hs-CRP)、白蛋白(Alb)、尿素清除指数(Kt/v)指标差异,分析血液透析患者发生营养不良的独立危险因
素。结果:营养正常组患者年龄、透析时间、BUN、hs-CRP及Kt/v<1.2 的比例均显著低于营养不良组,Hb、BMI、Alb 以及Kt/v≥ 1.2
的比例均显著高于营养不良组,差异均具有统计学意义(P 均<0.05);多因素分析显示,年龄>70 岁、透析时间>25 个月、Kt/v<
1.2 均是导致血液透析患者发生营养不良的独立危险因素(P均<0.05)。结论:终末期肾脏病患者的年龄、透析充分性以及透析时
间长短均是导致维持性血液透析并发营养不良的独立危险因素。 |
英文摘要: |
Objective:To analyze and explore the nutritional status of patients with end-stage renal disease and underwent maintenance
hemodialysis and its risk factors.Methods:82 patients with end-stage renal disease who had underwent the maintenance hemodialysis
in our hospital fromJanuary 2010 to January 2014 were selected and according to the modified quantitative subjective global assessment
(MQSGA), the selected patients were divided into the malnutrition group (>10 points) and the normal group. Then the age, the gender,
the dialysis duration, the body mass index (BMI), the hemoglobin (Hb), the blood urea nitrogen (BUN), the triglyceride (TG), the
high sensitive-C reactive protein (hs-CRP), the albumin(Alb) and the urea clearance index (Kt/v) in two groups were observed and compared,
and the independent risk factors of malnutrition of patients with end-stage renal disease and underwent maintenance hemodialysis
were analyzed.Results:Age, dialysis duration, BUN, hs-CRP and the ratio of Kt/v<1.2 in normal group were significantly lower than
those of the malnutrition group(P<0.05); HB, BMI, Alb and the ratio of Kt/v≥ 1.2 were significantly higher than those of the malnutrition
group (P<0.05); Multivariate analysis showed the age>70 years old, dialysis duration>25 months and Kt/v<1.2 were the independent risk
factors of malnutrition in patients with end-stage renal disease and underwent maintenance hemodialysis (P<0.05).Conclusion:The age,
the abundant dialysis and the dialysis duration are the independent risk factors of malnutrition in patients with end-stage renal disease and
underwent maintenance hemodialysis. |
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