卢耀军 赵瑞平 孙凯 李洪宇 张连枝.Flash双源CT冠脉成像联合心肌灌注显像对猪急性心肌梗死模型的诊断价值[J].现代生物医学进展英文版,2016,16(3):449-452. |
Flash双源CT冠脉成像联合心肌灌注显像对猪急性心肌梗死模型的诊断价值 |
Diagnostic Value of Flash Dual-source CT Coronary Imaging Combined withMyocardial Perfusion Imaging in Acute Myocardial Infarction Model of Pigs |
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DOI: |
中文关键词: 双源CT 冠脉 心肌灌注 心肌梗死 猪 |
英文关键词: Dual source CT Coronary Myocardial perfusion Myocardial infarction Pig |
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中文摘要: |
目的:探讨Flash 双源CT(DSCT)冠脉成像联合心肌灌注显像对猪急性心肌梗死模型的诊断价值。方法:使用明胶海绵栓塞
法建立5 只猪急性心肌梗死模型,使用DSCT 冠脉成像联合心肌灌注显像进行"一站式" 扫描得到冠脉图像和心肌灌注图像,并
与冠脉造影和病理染色相比较。结果:DSCT 得到的心肌灌注图像结果与病理染色相比较,敏感性为93%,特异性为91%,阴性预
测值为96%,阳性预测值为84%,Kappa 值为0.82;DSCT 得到的冠脉图像与冠脉造影相比较,敏感性为93%,特异性为81%,阴性
预测值为95%,阳性预测值为75%,Kappa 值为0.71。结论:DSCT 冠脉成像联合心肌灌注显像与组织病理学及冠脉造影一致性较
好,可以用于对猪急性心肌梗死模型的诊断。 |
英文摘要: |
Objective:To investigate the diagnostic value of flash dual-source CT (DSCT)coronary imaging combined with myocardial
perfusion imaging in acute myocardial infarction model of pigs.Methods:A total of 5 acute myocardial infarction models of pigs
were cultured by means of gelatin sponge embolization, which were scanned by DSCT and "one-stop" generated coronary imaging and
myocardial perfusion imaging and were compared with coronary angiography and pathology staining.Results:Compared with pathology
staining, the results of myocardial perfusion imaging are as follows: the sensitivity was 93%, the specificity was 91%, the negative predictive
value was 96%, the positive predictive value was 84%, and the Kappa value was 0.82; compared with coronary angiography, the results
of coronary imaging are as follows: the sensitivity was 93%, the specificity was 81%, the negative predictive value was 95%, the
positive predictive value was 75%, and the Kappa value was 0.71.Conclusion:DSCT coronary imaging combined with myocardial perfusion
imaging is in a good consistency with coronary angiography and pathology staining, which can be used for the diagnosis of acute
myocardial infarction model of pigs. |
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