| 郝娥娥 关键 许西琳 高岩 张中宏 王莎莎 王珊.新疆维吾尔族慢性阻塞性肺病患者疾病严重程度与体重指数的相关性分析[J].现代生物医学进展英文版,2016,16(1):95-98. |
| 新疆维吾尔族慢性阻塞性肺病患者疾病严重程度与体重指数的相关性分析 |
| Analysis of the Correlation of Body Mass Index with Disease Severity ofPatients with Chronic Obstructive Pulmonary Disease in Xinjiang Uygur |
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| DOI： |
| 中文关键词: 慢性阻塞性肺病 疾病严重程度 体重指数 |
| 英文关键词: Chronic obstructive pulmonary disease Disease severity Body mass index |
| 基金项目:国家自然科学基金项目(81360009) |
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| 中文摘要: |
| 目的：探讨新疆维吾尔族慢性阻塞性肺病(COPD)患者疾病的严重程度(包括临床症状、气流受限严重程度、急性加重风险)
与其体重指数(BMI)的相关性。方法：收集2013 年1 月至2014 年6 月新疆维吾尔自治区人民医院、石河子大学医学院第一附属
医院、喀什地区第一人民医院呼吸科门诊及住院COPD 患者110 例，分别对其临床症状、气流受限严重程度、急性加重风险进行
评估分级，运用Spearman 相关分析COPD 患者疾病严重程度与体重指数的相关性。结果：COPD 患者的肺功能分级越高，体重指
数越低，二者呈显著负相关(r=-0.583，P<0.05)；COPD患者的呼吸困难分级越高，体重指数越低，二者呈显著负相关(r=-0.673，P<0.
05)；不同肺功能分级和呼吸困难分级COPD患者的体重指数比较差异均有统计学意义(P<0.05)。COPD患者的急性加重风险越
高，其体重指数越低，二者呈显著负相关(r= -0.461，P<0.05)；高风险组COPD 患者的体重指数显著低于低风险组，差异有统计学意
义(P<0.05)。结论：新疆维吾尔族COPD 患者疾病的严重程度与其体重指数之间存在显著相关性，BMI越低，其病情越重。 |
| 英文摘要: |
| Objective:To investigate the association between disease severity of patients with chronic obstructive pulmonary disease
(including clinical symptoms, airflow limitation severity, exacerbation risk) and body mass index in Xinjiang Uygur population.Methods:110 cases of outpatients and hospitalized patients with COPD were collected from January 2013 to June 2014 in People's Hospital
of Xinjiang Uygur Autonomous Region, the First Affiliated Hospital of Shihezi University School of Medicine, the First People's
Hospital of Kashi. The clinical symptoms, airflow limitation severity and exacerbation risk were assessed, spearman correlation analysis
was used to analyze the correlation of disease severity of COPD patients with their BMI.Results:The higher classification of pulmonary
function in COPD patients, the lower body mass index, both showed a significant negative correlation (r=-0.583, P<0.05). The higher
classification of dyspnea in COPD patients, the lower body mass index, both showed a significant negative correlation(r=-0.673, P<0.05).
The higher the acute exacerbation risk in COPD patients, the lower body mass index, both showed a significant negative correlation(r=-0.
461, P<0.05). The BMI of high-risk group of patients with COPD was significantly lower than that of the low risk group, the difference
was statistically significant (P <0.05).Conclusion:There was a correlation between the severity of COPD patients with BMI of Xinjiang
Uygur. The lower the BMI, the more severe disease condition. |
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