| 陈建华 张乐蒙 罗永忠 王伟 姚定泉 易青 杨华.622 例肺癌患者远处转移临床特征的回顾性分析[J].现代生物医学进展英文版,2015,15(34):6693-6696. |
| 622 例肺癌患者远处转移临床特征的回顾性分析 |
| Metastasis Features of 622 Patients with Stage IV Primary BronchogenicCarcinoma and Retrospective Analysis of its Relationship withClinicopathologic Factors |
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| DOI： |
| 中文关键词: 肺癌 临床特征 远处转移 回顾性分析 |
| 英文关键词: Lung cancer Clinical characters Distant metastasis Retrospective analysis |
| 基金项目:湖南省卫生厅科研基金课题（B2011-090） |
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| 中文摘要: |
| 目的：探讨不同病理类型IV 期原发性支气管肺癌的远处转移特点。方法：回顾性分析我科收治的622 例诊断明确、资料完整
的IV 期肺癌患者，比较不同病理类型肺癌患者各器官远处转移发生率，并进行统计学分析。结果：622 例IV期肺癌患者中，鳞状
细胞癌188 例(30.2%)，腺癌275 例(44.2%)，小细胞癌130 例(20.9%)，大细胞癌5 例(0.8%)，腺鳞癌14例(2.3%)。平均年龄55.4 岁，
男女比例为2.60：1，高发年龄为40～60 岁。各器官远处转移发生率从高到低依次为：骨267 例(42.9%)，胸膜212 例(34.1%)，双肺
162例(26.0%)，脑148 例(23.8%)，肝132例(21.2%)，肾上腺53 例(8.5%)，心包50 例(8.0%)，皮下转移6 例(1.0%)，肌肉3 例(0.5%)，
眼球和脊髓各1 例(0.2%)。单器官转移共283 例(45.5%)，多器官转移共339 例(54.5%)，最多为6 个器官远处转移。结论：不同病理
类型肺癌有各自不同的远处转移特点及临床特征，应选择相应的检查并制定针对性治疗方案。 |
| 英文摘要: |
| Objective:To investigate the characteristics and regularity of the distant metastasis of stage IV primary bronchogenic
carcinoma with different pathological types.Methods:A total of 622 patients with stage IV lung cancer, with complete clinical and
pathological data, were investigated retrospectively. The distant metastasis rates of different pathological types of lung cancer were
analyzed and compared statistically.Results:Among 622 cases of stage IV lung cancer, there were 188 cases of squamous cell carcinoma
(30.2%), 275 cases of adenocarcinoma (44.2%), 130 cases of small cell carcinoma (20.9%), 5 cases of large cell carcinoma (0.8%), 14
cases of adenosquamous carcinoma (2.3%). The average age was 55.4 years old, and the male to female ratio was 2.60:1. Patients of 40
to 60 years old were most vulnerable to lung cancer. The incidence of distant metastases from high to low was: bone metastases in 267
cases (42.9%), pleural metastases in 212 cases (34.1%), double lung metastases in 162 cases (26%), brain metastases in 148 cases
(23.8%), liver metastases in 132 cases (21.2%), adrenal metastases in 53 cases (8.5%), pericardial metastases in 50 cases (8%),
subcutaneous metastasis in 6 cases (1%), muscle metastases in 3 cases (0.5%), eye and spinal cord metastases each in 1 cases (0.2%). A
total of 283 cases had single organ metastasis (45.5%), and the other 339 cases had multiple organ metastasis (54.5%). There was a
maximum of 6 distant organs metastasis.Conclusion:The distant metastasis and clinical characteristics were different according to the
different pathological subtypes of lung cancer. Physicians should better choose the suitable examination and the pertinence treatment. |
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