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目的：探讨几丁糖和透明质酸钠对宫腔防粘连效果及并发症的影响。方法：回顾性分析本院2013 年9月~2014年9 月收治的150 例人工流产患者的临床资料，均实施常规无痛人流手术，按照术前处理方式的不同分为空白对照组（50 例）和几丁糖组（50 例）、透明质酸钠组（50 例）。术后随访6 个月，观察两组的阴道流血持续时间和月经复潮时间，以及术后第14 d子宫内膜厚度和术后粘连发生情况、并发症发生情况，并进行比较。结果：术后几丁糖组和透明质酸钠组的阴道流血持续时间和月经复潮时间，以及术后第14 d天子宫内膜厚度和术后粘连发生情况、并发症发生率与空白对照组之间均存在统计学差异，各项指标均显著优于空白对照组，P＜0.05，但几丁糖组和透明质酸钠组二组间比较差异无统计学意义，P＞0.05。结论：对人工流产患者予以几丁糖和透明质酸钠处理均可以获得良好的临床效果，有效减少术后粘连以及各种并发症的出现。

英文摘要:

Objective:To explore the influence of chitosan and sodium hyaluronate on intrauteric adhesion and complications of obstetrics.Methods:A retrospective analysis was performed on clinical data of 150 cases of induced abortion patients in our hospital fromSeptember 2013 to September 2014. All of the patients were given conventional analgesia artificial abortion operation, and were divided into blank control group (50 cases) and chitosan group (50 cases), sodium hyaluronate group (50 cases) according to the preoperative treatment in different ways. After 6 months of follow-up, the duration of vaginal bleeding and menstruation time, and the incidence of uterine adhesion, thickness of endometrium 14 d days after operation, and the complications after operation was detected and compared.Results:In group of chitosan and sodiumhyaluronate group, the time of duration of vaginal bleeding and menstruation, endometrial thickness and the incidence of complications after 14 d days of operation, postoperative adhesion were statistically significant differences compared with blank control group , the indicators in the chitosan and sodium hyaluronate group were superior to those of the control group (P<0.05), but the difference between the chitosan group and sodium hyaluronate group was not statistically significant, P > 0.05.Conclusion:Chitosan and sodium hyaluronate have good clinical effect in treatment of artificial abortion patients, which can effectively reduce the postoperative adhesion and a variety of complications.

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