| 龚晓辉 曾建武 段建平 李启宇 甘拓域 陈丽霞.湘潭地区2013-2014 年手足口病病原监测结果分析[J].现代生物医学进展英文版,2015,15(30):5907-5909. |
| 湘潭地区2013-2014 年手足口病病原监测结果分析 |
| Etiological Analysis of Hand-Foot-Mouth Disease |
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| DOI： |
| 中文关键词: 手足口病 肠道病毒 柯萨奇病毒A16 肠道病毒71 |
| 英文关键词: Hand-foot-mouth disease Enterovirus Coxsackievirus A16 Enterovirus 71 |
| 基金项目:湘潭市科技局指导项目（zj20131016） |
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| 中文摘要: |
| 目的：分析2013-2014 年湖南省湘潭市手足口病（HFMD）病原体型别及分布特征，为进一步完善HFMD 的预防和治疗提供
依据。方法：采用RT-PCR方法，对571 例HFMD 患儿进行肠道病毒通用型核酸（EV-RNA）、EV71 及柯萨奇病毒A16（CA16）检
测。结果：2013年除EV71 及CA16 外其他EV核酸阳性率75.30%,明显高于EV71 的17.65%和CA16 的7.05%（P<0.05）,2014 年
EV71 型核酸阳性率为50.68%，明显高于CA16 的19.93%和其他EV 的29.39%（P<0.05）。重症HFMD 患儿EV71 感染率明显高
于轻症。结论：2013 年湘潭地区HFMD 患儿以除EV71 及CA16 外的其他EV 病毒感染为主，2014 年湘潭地区HFMD 患儿以
EV71 感染为主。 |
| 英文摘要: |
| Objective:To analyze the pathogenic type and the distribution characteristic of hand-foot-mouth disease (HFMD) in
Xiangtan District of Hunan Province from 2013 to 2014 and to provide the reference for preventing and controlling HFMD.Methods:The EV-RNA, EV71 and Coxsackievirus A16(CA16) were detected by reverse transcription-polymerase chain reaction(RT-PCR) method
in 571 children with HFMD.Results:In 2013, the positive rate (75.30%) of other EV except for EV71 and CA16 was significantly higher
than that(17.65%) of EV71 and that(7.05%) of CA16(P<0.05). In 2014, the positive rate(50.68%) of EV71 was significantly higher than
(19.93%) of CA16 and that (29.39%) of other EV（P<0.05）. The positive rate of EV71 in sever HFMD children was higher than that in
mild HFMD children.Conclusion:For HFMD children in Xiangtan district, the other EV except for EV71 and CA16 was the main
pathogen type in 2013, while EV71 was the main pathogen type in 2014. |
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