| 刘广林 刘明富 王怡 董海龙 陈敏 王韶双 路志红△.机器人辅助妇科手术术中气腹对患者肝肾功能影响的初步临床研究[J].现代生物医学进展英文版,2015,15(29):5655-5657. |
| 机器人辅助妇科手术术中气腹对患者肝肾功能影响的初步临床研究 |
| Pilot Study on the Effect of Pneumoperitoneum on Hepatic and RenalFunction during Robotic Laparoscopic Gynecologic Surgery |
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| DOI： |
| 中文关键词: 机器人辅助手术 气腹 肝功能 肾功能 |
| 英文关键词: Robotic surgery Pneumoperitoneum Hepatic function Renal function |
| 基金项目:国家自然科学基金项目（81070966）；贝朗麻醉科研基金项目（BBF-2013-009）；西京医院助推项目（XJZT10Y17） |
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| 中文摘要: |
| 目的：研究机器人辅助妇科手术中气腹对术者肝肾功能的影响。方法：择期开腹妇科手术和机器人辅助妇科手术患者各20
例，18-65 岁，体重指数18-30，美国麻醉医师协会分级1-2级。手术均在全身麻醉下进行。采用丙泊酚（1.5-2 mg/kg）和芬太尼（2-4
滋g/kg）进行全麻诱导。麻醉维持采用七氟烷和瑞芬太尼。术中维持Narcotrend 指数于40-60。分别于手术开始前和结束后30 min
抽取静脉血，测定血谷丙转氨酶、谷草转氨酶、尿素氮和肌酐水平并分析其变化。结果：与开腹手术相比，机器人辅助妇科手术气
腹后血谷丙转氨酶、谷草转氨酶、尿素氮和肌酐的升高更为明显（P均<0.05）。结论：机器人辅助妇科手术中长时间气腹可能引起
肝肾功能的异常。 |
| 英文摘要: |
| Objective:To compare the change of hepatic and renal function after open or robotic laparoscopic gynecologic
surgery.Methods:Patients scheduled for open or robotic laparoscopic gynecologic surgery were involved in this study (n=20). Inclusion
criteria included age between 18-30 yr, BMI between 18-30 kg/cm2 and ASA status 1-2. Anesthesia induction was done with propofol
（1.5-2 mg/kg）and fentanyl（2-4 ug/kg）. Anesthesia was maintained by sevoflurane and remifentanil. Narcotrend index was maintained at
40-60 during surgery. Venous blood sample was collected before and at 30min after surgery for assay of Alanine transaminase (ALT),
Aspartate transaminase (AST), Blood urea nitrogen (BUN) and Creatinine (Cr).Results:Conclusion:Compared with patients undergoing open
surgery, those undergoing robotic laparoscopic gynecologic surgery showed significant change of ALT, AST, BUN and Cr.
Long duration of pneumoperitoneum during robotic laparoscopic gynecologic surgery could lead to abnormal hepatic and renal function.
However, the clinical significance of this change is still unclear. |
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