| 张小兵 白利青 乔佳妮 吴菊 马骏.血脂与血尿酸浓度变化在老年脂肪肝患者诊断中的价值[J].现代生物医学进展英文版,2015,15(27):5333-5335. |
| 血脂与血尿酸浓度变化在老年脂肪肝患者诊断中的价值 |
| The Diagnosis Value of Blood Lipids and Blood Uric Acid ConcentrationChanges in Elderly Patients with Fatty Liver |
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| DOI： |
| 中文关键词: 脂肪肝 血脂 血尿酸 |
| 英文关键词: Fatty liver Blood lipids Blood uric acid |
| 基金项目: |
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| 中文摘要: |
| 目的：研究血脂与血尿酸浓度变化在老年脂肪肝患者诊断中的价值。方法：选取我院三年来健康体检时确诊为脂肪肝患者
的80 例为观察组，体检结果为健康正常人的80 例为对照组。测定两组总胆固醇、甘油三酯、血尿酸、高密度脂蛋白胆固醇、低密
度脂蛋白胆固醇的值，将检测结果进行对比。结果：两组检测结果对比，观察组的总胆固醇高于对照组的(x2=11.358，P=0.015)；观
察组的甘油三酯值高于对照组（x2=7.456，P=0.035）；观察组中的血尿酸，高于对照组值（x2=9.875，P=0.029）、低密度脂蛋白胆固醇
的值，高于对照组（x2=12.037，P=0.013），高密度脂蛋白胆固醇低于对照组（x2=5.149，P=0.041）。在轻、中、重度三组脂肪肝患者中，
中度脂肪肝患者的总胆固醇、甘油三酯、血尿酸、低密度脂蛋白含量高于轻度脂肪肝患者，高密度脂蛋白含量低于轻度脂肪肝患
者，P＜0.05，差异有统计学意义；重度脂肪肝患者的总胆固醇、甘油三酯、血尿酸、低密度脂蛋白含量高于中度脂肪肝患者，高密度
脂蛋白含量低于中度脂肪肝患者，P＜0.05，差异有统计学意义。结论：脂肪肝病变程度越大，脂肪肝患者总胆固醇、甘油三酯、血尿
酸、低密度脂蛋白胆固醇的值越高，高密度脂蛋白胆固醇的值越低，血脂与血尿酸浓度变化可作为诊断脂肪肝疾病的依据，可实
现早发现、早治疗，值得应用。 |
| 英文摘要: |
| Objective:To investigate the diagnosis value of the changes of blood lipids and blood uric acid concentration in elderly
patients with fatty liver.Methods:80 cases with fatty liver in our hospital were the observation group, while 80 health and normal cases
were the control group. The total cholesterol, triglycerides, uric acid, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol
of two groups was detected and compared.Results:The total cholesterol of observation group was higher than the control group
(x2=11.358, P=0.015); the triglycerides of observation group was higher than the control group(x2=7.456,P=0.035); the uric acid of observation
group was higher than the control group (x2=9.875,P=0.029); the low-density lipoprotein cholesterol of observation group was
higher than that of the control group（x2=12.037，P=0.013）, the high-density lipoprotein cholesterol of observation group was lower than
the control group(x2=5.149，P=0.041）, which had significant differences(P<0.05). In comparison of blood lipids and blood uric acid in the
groups of mild, moderate and severe fatty liver, the cholesterol, triglycerides, uric acid and low-density lipoprotein of moderate group
were higher than that of mild group, the high-density lipoprotein was lower than that of mild group; the value of cholesterol, triglycerides,
uric acid and low-density lipoprotein in severe groups were the highest and the value of high-density lipoprotein was the lowest in three
groups, and there were significantly statistical differences between any two groups (P＜0.05).Conclusion:The patients with greater degree
of fatty liver had higher level of the total cholesterol, triglycerides, uric acid, low-density lipoprotein cholesterol, and the lower
high-density lipoprotein cholesterol, suggesting that the lipids and uric acid concentration could be used as a basis for the diagnosis of fatty
liver disease, which could achieve early detection and early treatment and worth of clinic application. |
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