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目的：探讨影响乳腺癌患者预后的相关因素。方法：回顾性分析2008 年1 月～2009 年2 月我院收治的81 例乳腺癌患者的临床、病理及随访资料。结果：所有患者均手术治疗并经病理证实，年龄45 岁以上的乳腺癌患者的五年生存率为82.6％，显著高于45 岁及其以下者(45.7％，P<0.05)；肿瘤直径为3 cm 及其以下的乳腺癌患者的五年生存率为81.5％，显著高于肿瘤直径为3 cm 以上者(40.7％，P<0.05)；无淋巴结转移的乳腺癌患者五年生存率明显高于有淋巴结转移的乳腺癌患者(P<0.05)；I 期、II期、Ⅲ期、 Ⅳ期的乳腺癌患者五年生存率分别为93.8％、73.0％、52.9％、0％，不同临床分期的乳腺癌患者的五年生存率比较差异均有统计学意义(P<0.05)。结论：乳腺癌的治疗以手术为主，年龄、肿瘤大小、淋巴结转移、临床分期与患者的预后密切相关。

英文摘要:

Objective:To investigate the related factors affecting the prognosis of patients with breast cancer.Methods:A retrospective analysis was made on the clinical and pathological and follow-up data of 81 cases of breast cancer from Jan.2008 to Feb.2009 in our hospital.Results:All the cases received surgical treatment and were pathologicallly confirmed, the 5-year survival rate of breast cancer patients over 45 years old was 82.6%, which was significantly higher than those patients aged 45 years old and below (45.7%, P<0. 05). The 5-years survival rate of breast cancer patients whose tumor diameter were less than or equal to 3 cm was 81.5%, it was significantly higher than those whose tumor diameter were greater than 3cm (40.7%, P<0.05). The 5-year survival rate of breast cancer patients without lymph node metastases was significantly higher than those breast cancer patients with lymph node metastases in (P<0.05). The 5-year survival rates of breast cancer patients at stage I, stage II, stage Ⅲ, stage Ⅳ were 93.8%, 73%, 52.9%, 0%, significant differences were found in the 5-year survival rates between breast cancer patients at different clinical stages (P<0.05).Conclusion:Breast cancer was mainly treated by surgery, age, tumor size, lymph node metastasis, clinical stage were closely correlated with its prognosis.

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