| Objective:To analyze the clinical characteristics, key points of diagnosis and treatments, distribution of pathogenic
bacteria as well as the influencing factors of antibiotic use time of maxillofacial space infection (MSI).Methods:Medical records of 463
patients with MSI in West China Hospital of Stomatology, Sichuan University from 2009 to 2013 were studied retrospectively.
Chi-square test, binary logistic analysis were used to analyze the gender, age, admission body temperature, admission leukocyte count,
source of infection, bacteria culture, hospitalization duration, etc.Results:Among 463 patients, including 265 males (57.24%) and 198
females (42.76%), with an age range of 1 to 82 years (median 47years), most had a higher admission temperature, leucocyte number, and
neutrophilic granulocyte percentage than the normal. There were 206 patients (44.49%) accepting microbial culture test, while the rest
257 patients (55.51%) did not. A total of 127 pathogenic isolates were detected from 206 specimens, the majority were Streptococcus.
And the antibiotic use time had significant correlations with age, types of antibiotics, microbial culture results and basic diseases.Conclusion:Body temperature, leukocyte count and neutrophil percentage were all the important indications for infection. The antibiotics
should be used under the guidance of the microbial culture result, which could reduce the use time of antibiotics. |
