| 唐冰 刘晓桥 张萍 肖姗姗 梁琴.黄芪注射液对慢性心力衰竭患者BNP水平的影响[J].现代生物医学进展英文版,2015,15(22):4368-4370. |
| 黄芪注射液对慢性心力衰竭患者BNP水平的影响 |
| A Study on the Effect of Membranaceus Injection on the SerumLevel of BNPin Patients with Chronic Heart Failure |
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| DOI： |
| 中文关键词: 黄芪注射液 慢性心力衰竭 B 型脑利钠肽 |
| 英文关键词: Astragalus injection Chronic heart failure BNP |
| 基金项目:国家自然科学基金项目(30871074) |
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| 中文摘要: |
| 目的：探究黄芪注射液对慢性心力衰竭患者外周血清B 型脑利钠肽水平的影响。方法：选择2013 年12 月-2015 年1 月我院
收治的慢性心力衰竭住院患者334 例，按用药不同分为实验组和对照组。对照组患者采取常规药物口服治疗，实验组患者应用黄
芪注射液静脉滴注。观察并比较两组患者治疗前后外周血B 型脑利钠肽水平的变化情况。结果：治疗后，两组患者外周血B 型脑
利钠肽水平均明显下降，且实验组下降更明显，实验组Ⅰ 级、Ⅱ 级患者比例较对照组显著升高，差异均具有统计学意义(P＜0.05)。
结论：黄芪注射液能够降低慢性心力衰竭患者的外周血B型脑利钠肽水平，改善其心功能，值得临床推广应用。 |
| 英文摘要: |
| Objective:To explore the relevance of astragalus injection on the treatment of chronic heart failure and the relationship
of BNP level and the severity of heart failure.Methods:334 patients with chronic heart failure who were treated in our hospital from
December 2013 to January 2015 were selected and divided into the experimental group and the control group according to the different
treatment methods. The patients in the control group were treated with conventional oral medicine, while the patients in the experimental
group were treated with astragalus Injection. Then the changes of BNP levels in the two groups were observed and compared before and
after the treatment.Results:After treatment, the levels of BNP in peripheral blood of both groups were significantly decreased, and the
experimental group decreased more significantly with statistically significant differences (P<0.05). Compared with the control group, the
heart function of patients with treatment improved better in the experimental group (P<0.05).Conclusion:Astragalus injection could
significantly reduce the BNP level of patients with chronic heart failure and improve the heart function, which was worthy of clinical
application. |
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