吴多钢 郑利军 李国芳 史玮 牛瑜琳.常规血液透析和维持性血液透析对尿毒症患者心脏结构
及功能影响的对比研究[J].现代生物医学进展英文版,2015,15(21):4132-4134. |
常规血液透析和维持性血液透析对尿毒症患者心脏结构
及功能影响的对比研究 |
A Comparative Study on the Effects of Conventional Hemodialysis andMaintenance Hemodialysis on the Cardiac Structure and Function of Patientswith Uremia |
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DOI: |
中文关键词: 维持性血液透析 尿毒症 超声心动图 心电图 |
英文关键词: Maintenance hemodialysis Uremia Echocardiography Electrocardiogram |
基金项目:国家自然科学基金项目(81070583) |
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中文摘要: |
目的:采用超声联合心电图比较常规血液透析和维持性血液透析对尿毒症患者心脏结构及功能影响。方法:选取2014 年2
月至2014 年11 月我院收治的尿毒症患者110 例,将其随机分为实验组和对照组,每组各55例。对照组予常规血液透析,实验组
予维持性血液透析,采用碳酸氢盐透析液,透析液流量500-600 mL/min,每周透析2-3 次,每次透析4h。治疗后,通过超声心动图
测定室间隔厚度、左心室壁厚度、左心室舒张末内径、射血分数,采用心电图Q-T离散度分析Q-T离散度。结果:①治疗后,与对照
组相比较,实验组患者EF、FS 均显著降低,差异具有统计学意义(P<0.05),LVDd、LVDs、LVMI、LVH 值均明显升高,差异具有统
计学意义(P<0.05)。②治疗后,维持性血液透析患者的心电图Q-T 离散度与对照组相比较,差异有统计学意义(P<0.05)。结论:维
持性血液透析较常规血液透析能够更有效地改善尿毒症患者的心脏结构及功能。 |
英文摘要: |
Objective:To compare the effects of conventional hemodialysis and maintenance hemodialysis on the cardiac structure
and function of patients with uremia by cardiac ultrasound and electrocardiogram (ECG).Methods:110 patients with uremia admitted in
our hospital were selected, the patients were randomly divided into the experimental group and control group, 55 cases in each group, the
control group was given conventional hemodialysis, while the experimental group was treated with maintenance hemodialysis by bicarbonate
dialysate at flow rate 500-600 mL/min, 2-3 times per week, 4 h per dialysis. After the treatment, the interventricular septum thickness,
left ventricular wall thickness, left ventricular end diastolic diameter, ejection fraction were detected by echocardiography, and Q-T
dispersion was detected by ECG.Results:After treatment, compared with the control group, the EF, FS of experimental group were both
significantly decreased (P<0.05), while the LVDd, LVDs, LVMI, LVH were all obviously increased (P<0.05), the Q-T dispersion was
significantly improved (P<0.05).Conclusion:Maintenance hemodialysis could more effectively improve the cardiac structure and function
of patients with uremia. |
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