| 张珏颢 马正良 王小雨 彭慧萍 刘珊珊.老年患者全身麻醉术后认知功能障碍的影响因素分析[J].现代生物医学进展英文版,2015,15(21):4071-4073. |
| 老年患者全身麻醉术后认知功能障碍的影响因素分析 |
| Analysis of Influencing Factors of Postoperative Cognitive Dysfunction inElderly Patients After General Anesthesia |
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| DOI： |
| 中文关键词: 老年患者 全身麻醉 认知功能障碍 |
| 英文关键词: Elderly patients General anesthesia Postoperative cognitive dysfunction |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨分析老年非心脏手术患者全身麻醉术后认知功能障碍(POCD)的影响因素。方法：选择我院80 例老年行非心脏手
术患者，所有患者均给予全身麻醉手术，于术前及术后1、3 d 分别使用简易智能状态检查法（MMSE）评估患者认知功能，同时记
录行不同手术种类患者POCD 发生率并分析其年龄、麻醉时间、术中出血量、并发症情况及受教育程度等指标与POCD发生的相
关性。结果：80 例患者POCD发生率为30.0%，且不同种类手术中的发生率比较差异无统计学意义（P＞0.05）；POCD 组术后1d
MMSE 评分为较术前分明显下降，比较差异具有统计学意义（P＜0.05)；POCD组术后3 d及非POCD 组术后1、3 d MMSE 评分与
术前比较差异无统计学意义（P＞0.05）；Logistic 回归分析显示，患者年龄、文化程度、麻醉持续时间≥ 3 h、术中出血量≥ 350 mL及
合并高血压与POCD的发生具有显著相关性（P＜0.05）。结论：行全麻手术患者术后POCD 发病率较高，且患者高龄、文化程度
低、高血压合并症及麻醉持续时间长等是引起POCD发生的重要影响因素。 |
| 英文摘要: |
| Objective:To investigate the influence factors of postoperative cognitive dysfunction (POCD) in elderly patients with
non cardiac operation after general anesthesia.Methods:A total of 80 elderly patients with non cardiac operation in DrumTower Hospital
were selected, who were given general anesthesia operation, using the mini mental state examination (MMSE) function to evaluate the
cognitive function in the patients 1 d and 3 d before and after operation and to record incidence of POCD in different types of operation
and to analyze the correlation of the age, time of anesthesia, amount of bleeding during operation, the complications and the education
level of the patients with the occurrence of POCD.Results:The incidence of POCD of the 80 patients was 30%; there was no significant
difference in incidence among different types of operation(P>0.05); MMSE score of the POCD group 1d after operation was significantly
decreased compared with before operation, with significant difference (P<0.05); there were no statistical differences in MMSE score 3d
after operation in POCD group and 1d and 3d after operation in the non POCD group (P>0.05); Logistic regression analysis showed that
the patients' age (≥ 70 years), cultural level (≤ 9years), duration of anesthesia (≥ 3h), intraoperative bleeding volume (≥ 350ml) and
complicated with hypertension had a significant correlation with POCD (P<0.05).Conclusion:The incidence rate of POCD is higher for
the patients after general anesthesia operation, and the patients' age, low educational level, complications of hypertension and longer
duration of anesthesia are important influence factors for occurrence of POCD. |
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