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马姗 范玲玲 李宏增 张慜 杨永祥 王圣元 郭鹏 李川 李柱一△.321 例重症肌无力患者睡眠质量分析[J].现代生物医学进展英文版,2015,15(20):3933-3936.
321 例重症肌无力患者睡眠质量分析
Analysis of Sleep Quality in 321 Myasthenia Gravis Patients
  
DOI:
中文关键词: 重症肌无力  重症肌无力定量评分  匹兹堡睡眠质量指数
英文关键词: Myasthenia gravis  Quantitive myasthenia gravis score  Pittsburgh Sleep Quality Index (PSQI)
基金项目:国家自然科学青年基金项目(81301069)
Author NameAffiliation
马姗 范玲玲 李宏增 张慜 杨永祥 王圣元 郭鹏 李川 李柱一△ 第四军医大学唐都医院神经内科 
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中文摘要:
      目的:分析312 例重症肌无力患者病情稳定期的睡眠质量。方法:收集2013 年2 月—2014 年6 月第四军医大学唐都医院神 经内科门诊就诊的重症肌无力患者,应用匹兹堡睡眠质量指数(PSQI)对患者进行近1 月的睡眠质量问卷调查、重症肌无力定量 评分表(QMG)进行病情评分,以P< 0.05为有统计学意义,对MG 患者睡眠质量指数、各因子分进行分析研究。结果:符合重症肌 无力诊断标准、知情同意并纳入研究患者共有321 例,男156,女165。研究发现,多数重症肌无力患者有睡眠质量问题:性别与睡 眠质量、病情评定无相关性(P>0.05);重症肌无力患者睡眠质量问题主要表现为入睡时间、睡眠效率、睡眠障碍、日间功能方面。 结论:重症肌无力患者存在睡眠质量差这一问题。改善MG 患者肌无力症状的同时,应注重改善患者的睡眠质量。
英文摘要:
      Objective:To analyze the sleep quality in patients with myasthenia gravis.Methods:Clinical data of myasthenia gravis (MG) patients were collected in Outpatient Neurology Department, Tangdu Hospital, Fourth Military Medical University, from February 2013 to June 2014. All the applications were asked to fulfill the Pittsburgh Sleep Quality Index (PSQI) and quantitative myasthenia gravis score (QMG). P<0.05 was considered statistically significant.Results:The enrolled MG patients were 321, 156 males and 165 females. Most MG patients suffered fromsleep disorders. No significant difference was found in sleep quality and severe clinical symptoms in MG patients of different gender(P>0.05). The disorders of sleep quality mainly were sleep time, sleep efficiency, sleep disturbances, daytime function.Conclusion:Myasthenia gravis patients are in poor sleep quality. We should improve the symptoms of patients with myasthenia gravis, as well as patients’sleep quality.
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