| Objective:To explore the regulatory effect of estrogen combined with Danzhi Xiaoyao Capsule on the reproductive
endocrine and immune function of female patients with climacteric syndrome.Methods:60 female patients with climacteric syndrome
admitted in our hospital from May 2014 to September 2014 were selected and randomly divided into two groups, 30 patients in the
control group were treated by the clinical?routine of estrogen replacement, while the other 30 patients in the observation group were
treated by dang zi xiao yao capsules based on the use of estrogen replacement therapy. After treatment, the reproductive endocrine
hormone(E2, FSH, LH) levels, the ratio of T lymphocyte subsets(CD3+, CD4+, CD8+, CD4+/CD8+), the changes of IL-2 activity were observed
and compared between two groups.Results:After treatment, the E2, CD3＋, CD4＋, CD4＋/CD8＋ levels and IL-2 activity of both groups were
significantly higher than those before treatment (P<0.05), while the FSH, LH levels were obviously lower (P<0.05). Moreover, the E2,
CD3＋ , CD4＋ , CD4＋/CD8＋ levels and IL-2 activity of expreriment group after treatment were all significantly higher than those of the
control group(P<0.05), while the FSH, LH levels were obviously lower(P<0.05).Conclusion:Estrogen combined with Danzhi Xiaoyao
capsule could effectively regulate the reproductive endocrine hormone levels and improve the immune function of female patients with
climacteric syndrome, which was worthy of clinical application. |
