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周春容 胡帮聪 曹跃勇 郑婷 曾宪辉 崔长乐.直径大于3 厘米的周围型肺癌血流动力学的多排螺旋CT动态增强扫描研究[J].现代生物医学进展英文版,2015,15(18):3517-3519.
直径大于3 厘米的周围型肺癌血流动力学的多排螺旋CT动态增强扫描研究
Dynamic Enhanced Spiral CT Scan on the Hemodynamics of Diameter 3 cmabove the Peripheral Lung Cancer
  
DOI:
中文关键词: 周围型肺癌  血流动力学  螺旋CT  增强
英文关键词: Peripheral lung cancer  Hemodynamics  Spiral CT  Enhancement
基金项目:
Author NameAffiliation
周春容 胡帮聪 曹跃勇 郑婷 曾宪辉 崔长乐 宜宾市第二人民医院放射科泸州医学院附属医院放射科同济大学 
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中文摘要:
      目的:研究直径3 厘米以上周围型肺癌血流动力学的螺旋CT(电子计算机断层扫描,Computed Tomography)动态增强扫描 的特点。方法:选取我院收治的肿瘤直径>3 cm的周围型肺癌患者55 例,肺部腺瘤(良性)患者10 例,肺部炎性结节患者26 例。 分别进行螺旋CT 动态增强扫描,记录其CT 值、强化峰值(Peak enhancement,PH),绘制动态增强时间- 密度曲线,计算并比较曲 线最大增强线性斜率(steepes slope,SS)以及血流灌注量(blood perfusion, BP)。结果:肺部炎性结节患者的密度曲线在120 s达到 最大值;肺癌患者的密度曲线至65 s达到高峰;胸腺瘤患者的密度曲线变化不明显。肺癌组PH 平均值大于胸腺瘤组,差异有统计 学意义(P<0.05);胸腺瘤组PH 平均值小于肺部炎性结节组,差异有统计学意义(P<0.05);肺癌组SS 和BP大于胸腺瘤组,差异 有统计学意义(P<0.05);胸腺瘤组SS 和BP 小于肺部炎性结节组,差异有统计学意义(P<0.05)。结论:螺旋CT动态增强扫描能 够反映直径3 厘米以上周围型肺癌的血流动力学特点从而有助于在肺癌的诊断和鉴别诊断。
英文摘要:
      Objective:To study the hemodynamic characteristics of dynamic scanning of a diameter of 3 cm or more peripheral lung cancer enhanced spiral CT.Methods:55 cases of patients with peripheral lung cancer, thymoma (benign) of 10 patients, 26 cases of pulmonary inflammatory nodule in our hospital were selected. Under the dynamic enhanced spiral CT scan, recording its CT value, peak enhancement (PH), rendering dynamic time density curve, maximum enhancement steepes slope (SS) and blood perfusion (BP).Results:The density curve of patients in pulmonary inflammatory nodules group reached the maximum at 120 s, in lung cancer reached the maximum at 65 s, and in undulating thymoma group there was no change. The average value of PH in lung cancer group was significantly higher than that of the thymoma group (P<0.05); the average PH in thymoma group was significantly lower than that of the pulmonary inflammatory nodule group (P<0.05). Lung cancer group SS and BP is greater than the thymoma, the difference was statistically significant (P<0.05); Thymoma group SS and BP is less than pulmonary inflammatory nodule group, the difference was statistically significant (P<0.05).Conclusion:Dynamic enhanced spiral CT scan can reflect more than 3 cmin diameter of peripheral lung cancer hemodynamic characteristics so as to help in the diagnosis and differential diagnosis of lung cancer.
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