| 沈珍贤 曲衎衎 毛智群 朱培俊 黄海鹰.依达拉奉联合血栓通对急性脑梗死的疗效及对神经功能缺损和日常生活能力的影响[J].现代生物医学进展英文版,2015,15(17):3337-3339. |
| 依达拉奉联合血栓通对急性脑梗死的疗效及对神经功能缺损和日常生活能力的影响 |
| The Clinical Effect of Xueshuantong Combined With Edaravone inTreatment of Acute Cerebral Infarction and Its Impact on NeurologicalDeficits and Activities of Daily Living |
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| DOI： |
| 中文关键词: 依达拉奉 血栓通 急性脑梗死 神经功能缺损 日常生活能力 |
| 英文关键词: Edaravone Xueshuantong Acute cerebral infarction Neurological deficit Activities of daily living |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨依达拉奉联合血栓通治疗急性脑梗死（ACI）的临床疗效及对患者神经功能缺损和日常生活能力的影响。方法：将
我院2011 年1 月-2013 年1 月收治的98 例ACI患者按照入院先后顺序随机分为两组，每组各49 例，其中对照组在对症治疗基
础上加用依达拉奉，而观察组在对照组的基础上加用血栓通，对比两组临床疗效及患者神经功能缺损评分（NIHSS）、日常生活能
力（ALD）评分及不良反应发生率。结果：观察组总有效率为91.92%，显著高于对照组的71.43%（P<0.05）；观察组治疗后NIHSS 评
分为（10.18± 2.21）分，而ALD 评分为（57.42± 3.66）分，较对照组和治疗前均有显著改善（P<0.05）；两组不良反应发生率比较差异
无统计学意义（P>0.05）。结论：依达拉奉联合血栓通治疗ACI疗效显著，可明显改善患者神经功能缺损、提高日常生活能力，具有
较好的临床应用价值。 |
| 英文摘要: |
| Objective:To investigate the effect of Xueshuantong combined with edaravone in treatment of acute cerebral
infarction (ACI) and the impact on neurologic impairment and activities of daily living.Methods:98 cases of ACI patients in our hospital
from January 2011 to January 2013 were randomly divided into two groups according to admission order, and each group had 49 cases,
the control group was given edaravone on the basis of the symptomatic treatment while the observation group was given edaravone on the
basis of control group. The clinical efficacy, neurological deficit (NIHSS) score, activities of daily living (ALD) score changes and
incidence rate of adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was
91.92% significantly higher than 71.43% of the control group (P<0.05); after treatment, the NIHSS score of the observation group was
(10.18± 2.21) points, while ALD score was (57.42± 3.66) points, which significantly improved than before and the control group (P<0.
05); The incidence rate of adverse reactions between two groups was no significant difference(P>0.05).Conclusion:Edaravone combined
with Xueshuantong in treatment of ACI has good effect, and it can significantly improve patients' neurological function and activities of
daily living, which has better clinical value. |
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