| 王丁丁 周慧兰 宋青山 陈子林 王小艺.曲安奈德玻璃体注射治疗黄斑水肿的安全性长期随访分析[J].现代生物医学进展英文版,2015,15(16):3112-3114. |
| 曲安奈德玻璃体注射治疗黄斑水肿的安全性长期随访分析 |
| Long-termFollow-up of Safety of Intravitreous Injection with TriamcinoloneAcetonide on Macular Edema |
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| DOI： |
| 中文关键词: 曲安奈德 玻璃体注射 并发症 |
| 英文关键词: Triamcinolone acetonide(TA) Intravitreous injection Complications |
| 基金项目:广东省惠州市科技计划项目（20130802） |
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| 中文摘要: |
| 目的：观察2 mg、4 mg曲安奈德玻璃体注射治疗黄斑水肿的长期安全性。方法：将54 例黄斑水肿患者分别采用2 mg和4mg
不同剂量的曲安奈德玻璃体内注射，随访2 年，观察眼压、晶状体、眼内炎症、视网膜、玻璃体等并发症。结果：两种剂量曲安奈德
玻璃体内注射均可产生高眼压、白内障、非感染性眼内炎症；4 mg组白内障发生率明显高于2 mg 组,其余并发症未见明显差异;两
组患者均未出现严重、不可逆并发症。结论：2 mg 和4 mg 曲安奈德玻璃体注射治疗黄斑水肿均较安全，4 mg 剂量更容易发生白
内障，两种计量均需长期随访。 |
| 英文摘要: |
| Objective:To study the long-term safety of intravitreous injection with 2 mg and 4mg triamcinolone acetonide(TA) for
macular edema.Methods:54 cases of patients with macular edema were treated by intravitreous injection of 2 mg or 4 mg TA. The IOP,
lens, inflammation, retina and vitreous were followed up for 2 years for all cases.Results:Two doses of intravitreous injection with
triamcinolone acetonide could produce high intraocular pressure, cataract and non-infectious uveitis. The incidence of cataract of 4mg
group was significantly higher than that in 2 mg group, but there was no significant difference between two groups in other complications.
The serious, irreversible complications were not found in any patient.Conclusion:2 mg and 4 mg intravitreous injection of TA have the
same long-termclinical safety for macular edema, and need follow-up for a long time. The dose of 4mg is more likely to induce cataract. |
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