何茂锐 潘菁 曹永平 谢伶华 向明确△.枯草杆菌二联活菌肠溶胶囊预防艾滋病相关性腹泻的临床研究[J].现代生物医学进展英文版,2015,15(15):2938-2940. |
枯草杆菌二联活菌肠溶胶囊预防艾滋病相关性腹泻的临床研究 |
Prevention and Effect of Bacillus Subtilis and Enterococcue FaeciumEnteric-Coated Capsules for AIDS Associated Diarrhea |
|
DOI: |
中文关键词: 枯草杆菌二联活菌肠溶胶囊 HAART 艾滋病相关性腹泻 |
英文关键词: Bacillus Subtilis and Enterococcue Faecium enteric-coated capsules HAART AIDS associated diarrhea |
基金项目: |
|
Hits: 607 |
Download times: 0 |
中文摘要: |
目的:观察枯草杆菌二联活菌肠溶胶囊对艾滋病(AIDS)相关性腹泻的防治作用。方法:选择2013 年7 月至2014 年5 月在
我科门诊进行高效抗逆转录病毒(HAART)治疗的AIDS 患者80 例,随机分成对照组40 例和观察组40 例。对照组给予单用
HAART治疗,观察组在对照组的基础上联合使用枯草杆菌二联活菌肠溶胶囊,两组疗程均为24 周。治疗结束后观察两组的
HAART 疗效、AIDS 相关性腹泻的发生率,以及大便培养真菌感染情况。结果:观察组和对照组HAART治疗有效率分别为75%
和70%,两组比较差异无统计学意义(P>0.05)。对照组腹泻发生率明显高于观察组,比较差异有统计学意义(P<0.05),且对照组大
便培养真菌感染率明显高于观察组,比较差异有统计学意义(P<0.05)。结论:枯草杆菌二联活菌肠溶胶囊能有效预防AIDS相关
性腹泻的发生,并减少继发肠道真菌感染的发生。 |
英文摘要: |
Objective:To explore the prevention and effect of Bacillus Subtilis and Enterococcue Faecium enteric-coated capsules
for AIDS associated diarrhea.Methods:Selected 80 AIDS patients who were treated with highly active antiretroviral therapy(HAART) in
our department from July 2013 to May 2014, they were randomly divided into control group and observation group, with 40 patients in
each group. Control group was treated with HAART, while observation group was treated with HAART combined with
Bacillus Subtilis and Enterococcue Faecium enteric-coated capsules, the course of treatment was 24 weeks for two groups. After the treatment, observed the
effect of HAART, incidence of AIDS associated diarrhea and the status of stool culture infection of fungi in two groups.Results:Effective
rate of HAART in observation group and control group were 75%and 70%respectively, the difference was no statistically significant
(P>0.05). The incidences of AIDS associated diarrhea and stool culture infection of fungi in control group were significantly higher than
observation group, the differences were statistically significant (P<0.05).Conclusion:Bacillus Subtilis and Enterococcue Faecium enteric-
coated capsules can effectively prevent AIDS associated diarrhea and reduce the secondary intestine fungal infection. |
View Full Text
View/Add Comment Download reader |
Close |