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目的：探讨心理干预对维持性血透患者生活质量及肝肾功能的影响。方法：选择2012 年3 月到2014 年3 月在我院进行血液透析患者80 例，随机分为常规组和干预组各40 例，常规组进行常规干预，干预组在常规干预的基础上给予心理干预；采用全自动生化仪对血清尿素氮（BUN）、血清白蛋白（ALB）、血清肌酐（Scr）、血beta2 微球蛋白（beta2-MG）及血红蛋白（Hb）水平对进行检测，并对生活质量问卷MOSSF-36（SF-36）量表进行测评。对比两组干预前后生活质量评分和肝肾功能改善情况。结果：干预后干预组生理健康、心理健康及SF-36 总分明显高于干预前，差异有统计学意义（P<0.05），而对照组无显著性变化（P>0.05）；干预后两组BUN、Scr、beta2-MG水平均有降低，其中干预组降低更明显，差异均有统计学意义（P<0.05）；而两组ALB 和Hb 水平均有升上，其中干预组上升更明显，差异均有统计学意义（P<0.05）。结论：心理干预能明显提高维持性血透患者的生活质量，有效调节肝肾功能。

英文摘要:

Objective:To investigate the impact of psychological intervention on the quality of life and liver and kidney function in maintenance hemodialysis patients.Methods:Selected 80 patients with hemodialysis who were treated in our hospital from March 2012 to March 2014, they were randomly divided into conventional group and intervention group (with 40 patients in each group), the conventional group was treated with conventional intervention, while the intervention group was treated with psychological intervention on the basis of conventional intervention. The urea nitrogen (BUN), albumin (ALB), serum creatinine (Scr), blood beta-2 microglobulin (beta2-MG) and hemoglobin (Hb) level were detected by automatic biochemical analyzer, and evaluated the quality of life by questionnaire MOSSF-36 (SF-36), finally, we compared the quality of life and liver and kidney function of two groups before and after intervention.Results:Physical health, mental health and total score of SF-36 in intervention group after intervention was significantly higher than before intervention, the differences were statistically significant (P<0.05), but above indexes had no significant difference in conventional group. The BUN, Scr, 茁2-MG levels in two groups were decreased after the intervention, but the intervention group decreased more significantly, and the difference was statistically significant (P<0.05); While the ALB and Hb levels in two groups were increased after the intervention, and intervention group increased more significantly, the difference was statistically significant(P<0.05).Conclusion:Psychological intervention not only can significantly improve the quality of life but also effectively regulate liver and kidney function in maintenance hemodialysis patients.

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