| 韩莉 卢波 丁秋允 刘勇 张少光.盐酸非索非那定片联合胸腺肽对慢性荨麻疹患者风团及瘙痒情况的影响[J].现代生物医学进展英文版,2015,15(14):2738-2741. |
| 盐酸非索非那定片联合胸腺肽对慢性荨麻疹患者风团及瘙痒情况的影响 |
| Effect of Fexofenadine Combined with Thymic Peptide on Patients withChronic Urticaria's Wheal and Pruritus Condition |
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| DOI： |
| 中文关键词: 盐酸非索非那定片 胸腺肽 慢性荨麻疹 风团 瘙痒情况 影响分析 |
| 英文关键词: Fexofenadine slices Thymic peptide Chronic urticaria Wheal Pruritus condition Impact analysis |
| 基金项目: |
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| 中文摘要: |
| 目的：研究盐酸非索非那定片联合胸腺肽对慢性荨麻疹患者风团及瘙痒情况的影响分析。方法：选择2012 年7 月至2013
年7 月在我院接受治疗的慢性荨麻疹患者108 例作为研究对象。以数字法随机分成观察组（54 例）和对照组（54 例）。对照组患者
单纯服用盐酸非索非那定片，观察组在此基础上加用胸腺肽。对比两组疗效，风团和瘙痒症状总积分情况及不良反应。结果：观察
组的总有效率为72.22%（39/54），显著高于对照组的53.70%（29/54），差异有统计学意义（P＜0.05）。两组治疗后的症状总积分均
显著下降，但观察组治疗2，4 周后的症状总积分均显著小于对照组，差异均有统计学意义（P＜ 0.05）。观察组的总不良反应率为
9.26%（5/54），与对照组的22.22%（12/54）相比，差异无统计学意义（P＞ 0.05）。结论：盐酸非索非那定与胸腺肽联合治疗慢性荨麻
疹疗效较好，值得推荐。 |
| 英文摘要: |
| Objective:To study the effect of fexofenadine combined with thymic peptide on patients with chronic urticaria's wheal
and pruritus condition.Methods:108 cases of chronic urticaria patients from July 2012 to July 2013 in our hospital were selected as the
research objective, and were randomly divided into observation group (54 cases) and control group (54 cases). Patients in control group
were simply treated with fexofenadine,while the observation group were given giventhymic peptide in addition, the curative effect,
urticaria wheal and pruritus symptoms total score and adverse reactions of two groups were compared.Results:The total effective rate of
the observation group was 72.22%(39/54), significantly higher than 53.70% (29/54) in the control group, the difference was statistically
significant (P<0.05). The total score of symptoms of two groups after treatment both declined significantly, but the total integral score of
symptoms of observation group after 2, 4 weeks' treatment were significantly lower than that of the control group, the difference was
statistically significant (P<0.05). The total adverse reaction rate of observation group was 9.26%(5/54), while the control group was
22.22%(12/54), there was no statistically significant difference (P>0.05).Conclusion:Fexofenadine combined with thymic peptide on
patients with chronic urticaria is effective and is worth to be recommended. |
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