| 刘祎 镡丽霞 李清华 冯春 段江莹.肠内营养在直肠癌术后急性放射性肠炎中的临床应用研究[J].现代生物医学进展英文版,2015,15(13):2528-2531. |
| 肠内营养在直肠癌术后急性放射性肠炎中的临床应用研究 |
| Clinical Application Research of Enteral Nutrition for Acute RadioactiveEnteritis in Postoperative Patients of Rectal Cancer |
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| DOI： |
| 中文关键词: 肠内营养 直肠癌 术后 急性放射性肠炎 临床应用 |
| 英文关键词: Enteral nutrition Rectal cancer Postoperative Acute radioactive enteritis Clinical application |
| 基金项目:河北省卫生厅基金项目（20120594） |
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| 中文摘要: |
| 目的：研究肠内营养在直肠癌术后急性放射性肠炎中的临床应用。方法：选择2012 年7 月～2013 年7月在我院接受治疗的
104例直肠癌手术后发生急性放射性肠炎的患者作为研究对象。依照数字法随机分成观察组（51 例）和对照组（53 例）。对照组予
以（半）流质食物，观察组则予以能全力肠内营养支持治疗。分别在治疗前以及治疗后7d 测定血生化、营养以及电解质指标。结
果：经7d治疗后，观察组的前白蛋白（PA）、白蛋白（Alb）、视黄醇结合蛋白（RBP）及体重（BW）水平均显著高于治疗前以及对照
组，C反应蛋白（CRP）显著低于对照组，差异均有统计学意义（均P＜0.05）；但两组治疗后的总蛋白（TP）水平差异无统计学意义
（P＞0.05）；两组治疗前后的谷丙转氨酶（ALT）、血清碱性磷酸酶（AKP）、凝血酶原时间（PT）、胆红素（BIL）、尿素氮（BUN）、肌酐
（Cr）及血糖（Glu）等血生化指标以及钾离子（K+）、钠离子（Na+）、氯离子（Cl-）、钙离子（Ca2+）等电解质指标的差异均无统计学意义
（均P＞0.05）。结论：通过肠内营养治疗直肠癌手术后发生的放射性肠炎，可改善患者的营养状况，效果显著，值得推广。 |
| 英文摘要: |
| Objective:To study clinical application research of enteral nutrition for acute radioactive enteritis of postoperative
rectal cancer.Methods:104 cases of postoperative rectal cancer patients with acute radioactive enteritis fromJuly 2012 to July 2013 were
selected as the research object. They were divided into the observation group (51 cases) and control group (53 cases) according to the
randomnumber method. The control group was given (half) liquid foods; the observation group was given fully enteral nutrition support
treatment. Before and 7 d after treatment, blood biochemical indicators, nutrition condition index and electrolyte indicators were tested.Results:After 7d treatment, the PA, Alb, RBP and BW levels of the observation group were significantly higher than before treatment
and than those of the control group, the level of CRP was significantly lower than that of the control group, the difference had statistical
significance (P<0.05). But TP level difference of the two groups after treatment with no statistical significance (P>0.05). In the two
groups, ALT, AKP, PT, BIL, BUN, Cr and Glu blood biochemical indexes and K+, Na+, Cl- and Ca2+ electrolyte indexes' had no statistical
significant differences before and after treatment (P>0.05).Conclusion:Enteral nutrition treatment for radioactive enteritis that occurs after
rectal cancer surgery can improve the nutritional status of patients. It had obvious effect, which is worth of promotion. |
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