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目的：探讨内固定与植骨融合术治疗骨质疏松性椎体骨折的临床疗效。方法：回顾性分析我院2011 年7 月至2012 年7 月收治的80 例骨质疏松性椎体骨折患者的临床资料。根据固定方式，将37 例采用PMMA骨水泥强化椎弓根内固定的患者作为研究组，其余43 例单纯应用椎弓根内固定的患者作为对照组。收集两组患者的手术时间、术中出血量、术后疼痛程度、愈合时间等临床资料。评价患者手术前后侧位X 线片椎体高度和内固定效果。术后随访24个月。结果：两组患者的手术时间、术中出血量、住院时间及骨折愈合时间等无显著性差异（P>0.05）；研究组患者术后疼痛程度、椎体高度、内固定物松动及断裂情况等显著优于对照组，差异具有统计学意义（P<0.01）。结论：骨水泥强化椎弓根螺钉治疗骨质疏松性椎体骨折具有良好的临床效果，值得推广应用。

英文摘要:

Objective:To investigate the clinical efficacy of fixation and bone grafting of osteoporotic vertebral fractures.Methods:A retrospective analysis of clinical data in our hospital from July 2011 to July 2012 was performed in 80 cases of osteoporotic vertebral fractures. According to the fixed way, the 37 cases of patients treated with PMMA bone cement augmentation combined with pedicle screw fixation was admitted as the research group, and the remaining 43 cases of patients with a fixed simple application of pedicle was considered as the control group. Clinical data of all these patients including the operative time, blood loss, postoperative pain, healing time was collected. The vertebral height before and after surgery was measured by lateral X-ray radiography, and the fixed effect was evaluated. The patients were followed up for 24 months.Results:There was no significant difference (P>0.05) between the two groups in the operative time, blood loss, hospital stay or fracture healing time. In comparion of the postoperative pain, vertebral height, implant loosening and breaking between the two groups, the research group was superior to the control group, and the difference was statistically significant (P<0.01).Conclusion:Bone cement augmentation with pedicle screw fixation has good clinical effects on the osteoporotic vertebral fractures, and it is worthy of wide application in clinic.

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