| Objective:To investigate the effects of sevoflurane combined with lidocaine on the cardiac function of patients with
general anesthesia.Methods:70 cases of patients needed to carry on non cardiac surgery under the induction of general anesthesia were
selected, and randomly divided into two groups, 35 cases in each group. The control group was treated with pure sevoflurane induction of
general anesthesia for heart surgery; while the experimental group was treated with general anesthesia of sevoflurane joint lidocaine.
The cardiac function was observed and monitored respectively before the systemic narcotic induction (T1), 30 minutes after intubation
induction (T2), 1 hour after inducing intubation (T3) three time points. The peripheral vascular resistance (SVR), stroke volume (SV)
output, per minute output (CO), peak velocity (VpK), heart rate (HR), and net percentage ejection time (ET) % were compared at each
time point between the two groups.Results:① The level of SVR, SV, CO, VpK, HR, ET % level had no obvious change at T1 in the
experimental group and control group (P<0.05); ② compared with T1, the level of SVR, SV, CO, VpK, HR at T2 and T3 were
significantly lower in the two groups with statistical significance (P<0.05), and ET % was increased significantly (P<0.05); ③ compared
with that in the control group, the level of SVR, SV, CO, VpK, HR in experimental group at T2 and T3 were significantly higher, and the
difference was statistically significant (P<0.05), while ET% was significantly decreased, and the difference was statistically significant
(P<0.05).Conclusion:The general anesthesia with pure sevoflurane induction or sevoflurane combined with lidocaine affected the
cardiac function, but compared with the pure sevoflurane induction, sevoflurane combined with lidocaine had a minimal impact on
cardiac function, indicating it is more suitable for induction of general anesthesia surgery. |
