| 刘润宁 余长缨 应林燕 黎敏 李燕.孟鲁司特纳片联合沙美特罗替卡松粉吸入剂对儿童支气管哮喘的临床疗效[J].现代生物医学进展英文版,2015,15(8):1530-1533. |
| 孟鲁司特纳片联合沙美特罗替卡松粉吸入剂对儿童支气管哮喘的临床疗效 |
| Efficacy of Montelukast Sodiumand SALMETEROL Fluticasone PowderInhalation on Childhood Bronchial Asthma |
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| DOI： |
| 中文关键词: 孟鲁司特纳片 沙美特罗替卡松粉吸入剂 支气管哮喘 |
| 英文关键词: Montelukast Sodium SALMETEROL Fluticasone Powder Inhalation Bronchial asthma |
| 基金项目: |
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| 中文摘要: |
| 目的：探究孟鲁司特纳片联合沙美特罗替卡松粉吸入剂治疗儿童支气管哮喘的临床疗效并分析复发情况。方法：选取2011
年9 月至2012 年12 月在本院就诊并住院治疗的100 例支气管哮喘患儿，随机分成的对照组以及研究组，各50 例。对照组吸入
沙美特罗替卡松粉吸入剂，研究组给予孟鲁司特纳片联用沙美特罗替卡松粉吸入剂，观察哮喘的复发和控制情况。结果：用药治
疗后两组肺功能指标均有改善（P<0.05）；研究组用药第3、6 个月和停药6 个月时患儿肺功能较对照组改善更明显，差异均有统计
学意义（P<0.05）；两组患儿治疗后临床控制率均有显著的改善，但仅研究组差异有统计学意义（P<0.05）；研究组在用药3 个月、6
个月以及停药6 个月三个阶段临床控制率均高于对照组，而在用药6 个月以及停药6 个月两个阶段复发率均低于对照组，差异
均有统计学意义（P<0.05）。结论：孟鲁司特纳片联合沙美特罗替卡松粉吸入剂治疗儿童支气管哮喘疗效较单用沙美特罗替卡松粉
吸入剂治疗效果更好，复发率低。 |
| 英文摘要: |
| Objective:To explore the efficacy and recurrence of Montelukast Sodium and SALMETEROL Fluticasone Powder
Inhalation on childhood bronchial asthma.MethodsSelected 100 cases of children bronchial asthma from Sep,2011 to Dec, 2012 in our
hospital,which were randomly divided into two groups: control group and study group, 50 cases in each.The control group were taken
SALMETEROL Fluticasone Powder Inhalation for 6 months, while the study group were taken Montelukast Sodiumand SALMETEROL
Fluticasone Powder Inhalation. observed the recurrence and control of asthma.Results: Two groups of indices of pulmonary function were
improved after drug treatment. The lung function of study group was obviously improved than control group by 3 months, 6 months,and 6
months after discontinuation, the differences were statistically significant (P<0.05); The clinical control rates have improved significantly
in two groups,but only the study group had significant difference(P<0.05). The clinical control rate of study group was higher than that of
control group by 3 months, 6 months, and 6 months after discontinuation, and the recurrence rate was significantly lower than the control
group by 6 months, and 6 months after discontinuation (P<0.05), the differences were statistically significant (P<0.05).Conclusion:Montelukast Sodiumand SALMETEROL Fluticasone Powder Inhalation on childhood bronchial asthma have obvious curative effect and
low recurrence rate than treated with SALMETEROL Fluticasone Powder Inhalation alone. |
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