周叶 彭利 李建华 晏沐阳.BMI 及 LDL-C 水平与冠脉慢血流的相关性研究[J].现代生物医学进展英文版,2015,15(7):1201-1204. |
BMI 及 LDL-C 水平与冠脉慢血流的相关性研究 |
Correlation between LDL-C, BMI and Coronary Slow Flow |
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DOI: |
中文关键词: 冠状动脉慢血流现象 低密度脂蛋白 胆固醇 身体质量指数 危险因 素 |
英文关键词: Coronary slow flow phenomenon Low-density lipoprotein Body mass index Risk factor |
基金项目:国家自 然科学基金项目( 81073093) |
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中文摘要: |
目的: 探讨低密度脂蛋白 胆固 醇及身高体重指数与 冠状动脉慢血流现象( Coronary slow flow phenomenon,CSFP)的相关性。
方法: 在我院 2013 年上半年因 不典型胸痛行冠脉造影术患者中, 选取冠脉官腔无明显狭窄( <40 %)且至少一支冠脉根据校正的
TIMI 血流分级方法被评为 慢血流的患者进入慢血流组( CSFP 组)79 例 , 选取同期无明显狭窄且血流速度正常的患者 71 例为 对
照组, 对两组入院各项常规检查检验指标进行分析, 筛 选导致冠脉慢血流的危险因 素。 结果: 在两组比较中, CSFP 组的慢血流组
吸烟率、身体质量指数( Body Mass Index, BMI)、甘油三酯( Triglyceride, TG)、低密度脂蛋白胆固醇( Low density lipoprotein cholesterol, LDL-C)、尿酸( Uric acid, UA)水平明显高于对照组;亚组分析中显示 BMI、LDL-C 水平随受累 血管数量增多呈上升趋势,且
具有统计学意义; 经回归分析,显示 BMI、LDL-C 水平的升高对冠脉慢血流的发生有显著影响, 且与冠脉血流速度(帧数)呈正相
关。 结论: BMI、 LDL-C 水平与冠脉慢血流的发病的密切相关。 |
英文摘要: |
Objective:The aim of this research is to study the correlations between LDL-C, BMI and coronary slow flow phenomenon (CSFP).Methods:The 1 50 patients with chest pain, who were underwent coronary angiography, were divided by corrected TIMI
frame count(CSFP was defined as frame count >27) into CSF group(79) and control group(71). Body mass index (BMI), age, gender, history of smoking, hypertension, diabetes and hyperlipidemia were recorded and the total cholesterol (TC), triglyceride (TG), Low-density
lipoprotein (LDL-C), high-density lipoprotein (HDL-C), uric acid (UA), creatinine (Cr), left ventricular ejection fraction (EF), Systolic
blood pressure(SBP) and Diastolic blood pressure(DBP) were measured on admission.Results:The smoking rate, BMI, TG, LDL-C, UA
was significantly higher in the patients with the CSF group than the control group. BMI, LDL-C in the CSF group increased significantly
with increasing vessel involvement. The logistic regression analysis showed that BMI and LDL-C were the influence factor for coronary
slow flow, and were positively correlated with CSFP.Conclusion:CSFP is associated with BMI and LDL-C. |
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