| 薛 松 刘 昶 纪艳超 万会魁 崔 磊 姜 龙.骨髓间充质干细胞在脱细胞真皮基质再生过程中的初步研究[J].现代生物医学进展英文版,2015,15(5):998-1000. |
| 骨髓间充质干细胞在脱细胞真皮基质再生过程中的初步研究 |
| The Preliminary Study of Regeneration Process in Bone MarrowMesenchymal Stem Cells on Acellular Dermal Matrix |
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| DOI： |
| 中文关键词: 骨髓间充质干细胞 脱细胞真皮基质 |
| 英文关键词: Acellular dermal matrix Bone marrow mesenchymal stem cells |
| 基金项目: |
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| 中文摘要: |
| 较大的腹壁缺损需要应用 补片 修复来缓解腹横筋膜的张力， 人工合成补片 的应用 一定程度上实现了 无张力 修补的目 的， 但
它在腹壁外科应用中有诸多的并发症, 诸如复发率高， 腹腔黏连，肠穿孔导致腹膜炎， 侵袭性肠瘘等影响患者术后的正常生活，而
脱细胞真皮基质(Acellular dermal matrix, ADM)作为 一种新型的生物材料应用在腹壁外科中能解决上述人工合成补片 所带来的
并发症发挥强大作用 且能与 周围 组织较好的融合， 最后改建成宿主自 身组织已并在多 学科领域中广泛应用； 骨髓间 充质干细胞
(Bone marrow mesenchymal stem cells,BMSCs)能参与 组织自我修复， 并能分化成为 多 种功能细胞， 分泌各种生长因 子，在 ADM 内
源性转归过程中可发挥作用。 本文就对骨髓间充质干细胞在 ADM 生物补片 应用 于临床疝修补术中转归机制的研究做一综述。 |
| 英文摘要: |
| To repair larger abdominal wall defects, there is need to use man-made patches of synthesis. Because, to some extent,
their application can help reach the purpose of tensionless. The man-made pitches of synthesis have many complications used in Abdominal wall surgery, such as high rate of relapse, intraperitoneal adhesion led to peritonitis, and invasive intestinal fistula, which affect the
postoperative patients with normal life, but Acellular dermal matrix as a new kind of biological materials, can help solve those problems
and can integrate with the organization well instead of man-made patches, even though in many different disciplines. Bone marrow mesenchymal stem cells play an important role in participating tissue repair, secreting multiple cell growth factors. This review deseribes the
preliminary study of the process of regeneration in Bone marrow mesenchymal stem cells on Acellular dermal matrix. |
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