孙雪竹 卢美松 李萌 邹丽红 邓 锁.子宫内膜息肉研究进展[J].现代生物医学进展英文版,2015,15(5):985-987. |
子宫内膜息肉研究进展 |
Research Progress of Uterine Endometrial Polyps |
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DOI: |
中文关键词: 子宫内 膜 息肉 综述文献 |
英文关键词: Endometrium Polyp Review of the literature |
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中文摘要: |
子宫内 膜息肉( endometrial polyps, EMP)由子宫内 膜腺体和含有厚壁血管的纤维化内 膜间 质构成, 是局部子宫内 膜过度增
生形成的有蒂或无蒂的赘生物。 子宫内 膜息肉 是最常见的子宫内 膜病变之一, 临床表现为 子宫不规则 出血, 或月 经量增多、不孕、
绝经后出 血等, 也可无明显临床症状。 子宫内 膜息肉 多 数属良性病变,但其可恶变性已经被证实。 子宫内 膜息肉 的发病机制目前
尚不明确,传统观点认为其与慢性子宫内 膜炎症有关, 属慢性炎症范畴, 即为生物致炎因 子及长期反复机械性刺激所致的反应性
增生物; 近年来随着分子生物学研究的深入, 发现子宫内 膜息肉 的发生与 可能与激素调控下增殖与 凋亡失衡相关。 近来随着宫腔
镜检查技术的推广及激素补充治疗 人数的增多 , 子宫内 膜息肉 的发病率及检出 率逐渐增加, 加之经刮宫或电切治疗 后复发率非
常高, 因 此, 子宫内 膜息肉 越来越受到临床医生的重视, 现将子宫内 膜息肉 的研究进展作一综述。 |
英文摘要: |
Composition of uterine endometrial polyps by endometrial glands and contains thick wall vessel fibrosis endometrial
stromal, local endometrial hyperplasia formation in the presence or absence of a pedicle vegetations. Endometrial polyps endometrial
lesion is one of the most common, the clinical manifestations of irregular uterine bleeding, or menorrhagia, infertility, postmenopausal
bleeding, with no obvious clinical symptoms. Endometrial polyps most benign lesions, but the wicked degeneration has been confirmed.
The pathogenesis of endometrial polyps is unknown, the traditional view is that it is associated with chronic endometrial inflammation, is
a chronic inflammation category, the biological proinflammatory cytokines and repeated mechanical stimulation reaction induced by
growth; In recent years, with the development of molecular biology research, showed that the occurrence of uterine endometrial polyps
and may be associated with proliferation and apoptosis imbalance of hormone regulation. In recent years, with the increasing number of
promotion and hormone replacement therapy by hysteroscopy technology, endometrial polyp incidence rate and detection rate of
increase, combined with curettage or resection after treatment the recurrence rate is very high. Therefore, endometrial polyps more and
more by the clinician's attention, the research progress of endometrial polyps will be reviewed. |
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