| 常丽丽 巩义春 曹留霞 董丽娟 马朋林.红细胞分布宽度与 ICU 院内感染的相关性研究[J].现代生物医学进展英文版,2015,15(5):915-917. |
| 红细胞分布宽度与 ICU 院内感染的相关性研究 |
| Correlation of Red Blood Cell Distribution Width and NosocomialInfections in ICU |
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| DOI： |
| 中文关键词: 院内 感染 红细胞分布宽度 ROC 曲线 |
| 英文关键词: Nosocomial infections in ICU Red blood cell distribution width ROC curve |
| 基金项目: |
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| 中文摘要: |
| 目的： 探索红细胞分布宽度（ RDW）与 ICU 院内 感染的相关性。 方法： 根据 2001 年卫生部颁布的医院感染诊断标准，筛 选出
2011 年 1 月 至 2013 年 12 月 在 ICU 住院发生院内 感染的 224 例患者，与 同 期在 ICU 住院未发生院内 感染的患者 232 例， 收集相
关临床资料[年龄、性别 、既往合并高血压、冠心病史、慢性病（ APACHEⅡ ）评分、住院时间 、预后 ]及 RDW 等实验室指标（连续收集
入 ICU 前三天的实验指标取平均值）， 分析 RDW 与 院内 感染发生的相关性。 结果： 与对照组 RDW（ 12.18± 1.08）%相比， 院内 感染
组 RDW（ 13.52± 2.01）%明显升高， 差异有统计学意义(P <0.01)。多 因素 logistic 回归分析显示， RDW 是院内 感染的独立预测因素
（ OR=4.75， 95% CI: 3.27～ 6.91 , P<0.01)。 RDW 界值为 1 2.81 %， RDW 的 ROC 曲线下面积为（ 0.76± 0.02）% ， 95% CI： 0.71～ 0.80，
诊断院内 感染的敏感性为 56.65 %， 特异性为 85.75 %。 结论： RDW 与 ICU 院内 感染独立相关， 是 ICU 院内 感染的独立预测因
素。 |
| 英文摘要: |
| Objective:To explore the correlation between red blood cell distribution width (RDW) and nosocomial infection in
ICU.Methods:According to the diagnostic criteria of nosocomial infections issued by the Ministry of Health in 2001 . Screened two hundred and twenty-four patients with nosocomial infections admitted to our hospital patients in the ICU from January 201 1 to December
201 3, with the same period, two hundred and thirteen patients without nosocomial infection in the ICU. Their clinical data [Age, Gender,
Hypertension, Coronary heart disease, Chronic disease (APACHE Ⅱ ) score, Length of stay, the prognosis] and RDW et other laboratory
indicators (The averaged value of experiments indicators were collected continuously into the ICU three days before) were recorded. Analyzing the correlation between RDW and nosocomial infections in ICU.Results:The RDW in the group of nosocomial infection was
(1 3.52 ± 2.01)%, it increased significantly compared with that in the control group (P<0.01 ). Multivariate logistic regression analysis
showed that, the RDW was an independent predictor of nosocomial infection (OR=4.75, 95 % CI: 3.27 ~ 6.91, P<0.01). The RDW
threshold value is 1 2.81 percent and the RDW area under the ROC curve was (0.76 ± 0.02) %, (95% CI: 0.71 ~ 0.80), a diagnostic sensitivity was 56.65 % and a specificity was 85.75 % for the nosocomial infections in ICU.Conclusion:RDW is independently correlated with
the nosocomial infections in ICU, and is thus an independent predictor for the nosocomial infections in ICU. |
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