| 刘海岭 王妍 张明焕 李蕊 徐占彪.钼靶 X 线摄片联合肿瘤相关标志物检测对乳腺癌的诊断价值[J].现代生物医学进展英文版,2015,15(5):912-914. |
| 钼靶 X 线摄片联合肿瘤相关标志物检测对乳腺癌的诊断价值 |
| Diagnostic Value of X-ray Combined with Detection of Tumor-relatedMarkers in Serum of Breast Cancer |
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| DOI： |
| 中文关键词: 乳腺癌 钼靶 X 射线 肿瘤相关标志物 血清学检查 |
| 英文关键词: Breast cancer X-ray Tumor-related Markers Serum detection |
| 基金项目: |
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| 中文摘要: |
| 目 的： 探讨乳腺钼靶 X 射线摄片 与 血清糖类抗原 15-3（ CA15-3）、癌胚抗原（ CEA）和骨桥蛋白（ OPN）联合检测对乳腺癌的
临床诊断价值。 方法： 选择在我院经手术和病理证实为乳腺癌的患者 60 例作为 研究组，另 选取 60 例健康体检者作为对照组。 分
别 检测两组的血清 CA15-3、CEA 和 OPN 水平，并采用 乳腺钼靶 X 射线检查。 比较 X 射与 血清学检测单独检测及联合检测的阳
性率。 结果： 研究组患者血清 CA15-3、 CEA 及 OPN 水平均显著高于对照组，差异具有统计学意义（ P<0.05）； 血清 CA1 5-3、 CEA、
OPN 和钼靶 X 射线摄片 联合检测的敏感性显著高于单独检测， 差异具有统计学意义（ P<0.05）。 结论： 对乳腺癌患者进行钼靶 X
射线摄片及肿瘤相关标志物检测可提高阳性检出 率， 有利于乳腺癌的早期诊断及治疗。 |
| 英文摘要: |
| Objective:To investigate the diagnostic value of mammography X-ray radiography and serum detection of carbohydrate antigen 15-3 (CA15-3), carcinoembryonic antigen (CEA) and osteopontin (OPN) for breast cancer.Methods:60 cases with breast
cancer who were treated in our hospital were selected as the study group, and 60 healthy volunteers were selected as a control group. The
two groups were detected in serum CA15-3, CEA and OPN levels and the use of mammography X-ray examination. Comparison of
X-ray-positive rate and serology testing and joint detection alone.Results:The study group serum CA15-3, were significantly higher than
CEA and OPN water, the difference was statistically significant(P<0.05); serum CA1 5-3, CEA, OPN and mammography X-ray radiography combined detection significantly higher detection sensitivity alone, the difference was statistically significant (P<0.05).Conclusion:Radiography and tumor-associated markers for breast cancer patients concluded the X-ray mammography can increase the positive detec-
- tion rate for early diagnosis and treatment of breast cancer. |
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