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刘厚广 李峥 霍姗姗 陈木柯 葛玲 徐娜.蓝科肤宁联合胶原贴敷料治疗颜面再发性皮炎的临床观察[J].现代生物医学进展英文版,2014,14(36):7096-7099.
蓝科肤宁联合胶原贴敷料治疗颜面再发性皮炎的临床观察
Clinical Observation on the Velvetfeeling Combined with Collagen Dressingin the Treatment of Facial Recurring Dermatitis
  
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中文关键词: 颜面  再发性皮炎  蓝科肤宁  胶原贴敷料  临床疗效
英文关键词: Facial  Recurring  Dermatitis  Velvetfeeling  collagen dressing  Clinical efficacy
基金项目:厦门市卫生局资助研究经费(3502Z20130190)
Author NameAffiliation
LIU Hou-guang, LI Zheng, HUO Shan-shan, CHEN Mu-ke, GE ling,XU Na 福建中医药大学附属厦门市第三医院皮肤科 
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中文摘要:
      目的:探讨蓝科肤宁联合胶原贴敷料治疗颜面再发性皮炎的疗效和安全性。方法:将90 例入选的颜面再发性皮炎的患者随 机分成治疗组、对照1 组和对照2 组,每组各30 例。治疗组给予蓝科肤宁湿敷,早晚各一次,同时给予胶原贴敷料每晚1 次,连用 4 周;对照1 组外用蓝科肤宁湿敷;对照2 组外用胶原贴敷料每晚1 次,连用4 周。治疗结束后4 周,观察和比较各组患者的主观 症状感觉、皮损情况及不良反应的发生情况。结果:所有患者均按要求完成整个疗程。治疗4 周后,三组患者的症状评分均显著低 于治疗前,且治疗组的症状评分显著低于对照2 组(P<0.001),而与对照1 组比较差异无统计学意义(P>0.05)。治疗组、对照1 组和 对照2 组的临床有效率分别为93%、90%、63%,治疗组、对照1 组均显著高于对照2 组(P<0.05),而治疗组和对照1 组之间比较差 异无统计学意义(P>0.05)。三组不良反应的发生率比较均无统计学差异(P>0.05)。结论:蓝科肤宁联合胶原贴敷料治疗颜面再发性 皮炎的疗效更好,安全性高。
英文摘要:
      Objective:To investigate the curative effect and safety of Velvetfeeling combined with collagen dressing for facial recurring dermatitis.Methods:90 patients with facial recurring dermatitis were randomly divided into three groups, 30 patients in each group. The patients of treatment group were treated with Velvetfeeling every morning and evening, as well as collagen dressing every evening. The control group 1 was treated with Velvetfeeling alone. The control group 2 was treated with collagen dressing alone. The patients of the three groups were treated for 4 weeks. At the 4th week after the treatment, the subjective symptom, skin lesion, and incidence of adverse reaction were observed and compared between different groups.Results:All the patients completed the whole course of treatment. At the 4th week after the treatment, the symptom scores of three groups were significantly lower than those before treatment, and the symptomscore of treatment group was significantly lower than that of control group2 (P<0.001), while there was no statistically significant difference compared with control group 1 (P>0.05). The effective rates of treatment group, control group 1 and control group 2 were 93%, 90% and 63% respectively. The effective rates of treatment group and control group 1 were significantly higher than that of control group2 (P<0.05), and no statistical difference was found between treatment group and control group 1(P>0. 05). In addition, no statistical difference was observed in the incidence of adverse reactions between different groups.Conclusion:Velvetfeeling combined with collagen dressing had a better curative effect and high security in the treatment of facial recurring dermatitis than Velvetfeeling or collagen dressing alone.
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