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目的：探讨纤维桩树脂核修复老年残根残冠的疗效及对炎性因子的影响。方法：抽取2012 年1 月至2013 年4 月期间行老年残根残冠修复的患者80 例，共92 颗患牙，按随机数字表法分为研究组和对照组各40 例，其中研究组患牙47 颗，采用纤维桩树脂核修复；对照组患牙45 颗，采用金属铸造桩核修复。收集两组患者的血清和龈沟液样本，采用酶联免疫吸附法（Enzyme-Linked Immunosorbnent Assay, ELISA）分别检测两组的IL-8、IL-6 及TNF-琢水平。对比两组疗效及炎性因子水平。结果：研究组治疗患牙总体成功率明显高于对照组，失败率明显低于对照组（P＜0.05）；研究组不同牙位的治疗成功率均较对照组高，但差异不明显（P＞0.05）；修复前两组的IL-8、IL-6 及TNF-琢的水平差异不明显；研究组修复后1 周、1 个月及1 年的IL-8 和IL-6 水平均明显低于对照组（P＜0.05），研究组修复后1 年的TNF-琢水平明显低于对照组（P＜0.05），两组患者修复后1 周和修复后1月的TNF-琢水平相差不大（P＞0.05）；重复测量方差分析结果显示，两组IL-8、IL-6 及TNF-琢的水平均随着修复时间的延长而降低（P＜0.05）。结论：纤维桩树脂核修复老年残根残冠具有更好的疗效，对降低牙龈沟液中炎性因子水平的作用明显，值得在临床上应用和推广。

英文摘要:

Objective:To explore the curative effect and the effects on inflammatory factors of glass fiber post and core in the repair of elderly residual roots and crown.Methods:80 patients of elderly residual roots and crown who accepted treatment from January 2012 to April 2013, a total of 92 offending teeth were included in this study. These patients were divided into the research group and control group by random number table method, each group had 40 patients. The research group had 47 offending teeth which were treated with glass fiber post and core and the control group had 45 offending teeth which were treated with metal post. The samples of serum and gingival crevicular fluid were collected. The level of IL-8, IL-6 and TNF-alpha were examined by ELISA, the curative effect and inflammatory factor level were compared between two groups.Results:The total success rate of the research group was significantly higher and the failure rate was significantly lower than that of the control group (P＜0.05). The success rates of different dental areas in research groups were all higher than the control group, but the differences were not significant (P＞0.05). The level of IL-8, IL-6 and TNF-alpha presented no obvious difference between two group before treatment. The level of IL-8 and IL-6 of research group were significantly lower than in the control group after 1 week,1 month and 1 year post treatment (P＜0.05). The level of TNF-alpha of research group was significantly lower than that of the control group after 1 year (P＜0.05). The level of TNF-alpha showed no significant difference between the two groups after 1 week and 1 month. The results of the ANOVA for repeated measurement showed that the level of IL-8, IL-6 and TNF-alpha of both groups decreased with the extension of treatment time (P＜0.05).Conclusion:Glass fiber post and core has better curative effect in the repair of elderly residual roots and crown, and it has obvious effect on reducing the level of inflammatory factors in gingival groove liquid, it is worthy of popularization and application in clinic.

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