| 李金梅 焦林君 乌日娜 商进 杨越楠.308 nm 准分子光联合中药擦剂治疗白癜风的临床疗效观察[J].现代生物医学进展英文版,2014,14(35):6880-6882. |
| 308 nm 准分子光联合中药擦剂治疗白癜风的临床疗效观察 |
| Comparision of the Clinical Efficacy of 308 nm Excimer Lamp Combinedwith Topicas in the Treatment of Vitiligo in Inner Mongolia |
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| DOI： |
| 中文关键词: 白癜风 308 nm 准分子光 复方补骨脂酊 临床疗效 |
| 英文关键词: Vitiligo 308 nm excimer lamp Psoraleae tincture Clinical efficacy |
| 基金项目:国家自然科学基金项目 (81 160189) |
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| 中文摘要: |
| 目 的： 观察 308 nm 准分子光联合外用复方补骨脂酊治疗内 蒙古地区稳定期白癜风的疗效。 方法： 选取稳定期白癜风患者 60
例， 共 133 片 皮损。将其随机分成 2 组： A 组单用 308 nm 准分子光治疗； B 组给予 308 nm 准分子光联合复方补骨脂酊治疗。复方
补骨脂酊治疗每日 两次， 光疗频率每周 1 次， 10 次一疗程，共 2 疗程， 每次疗程结束后拍照、疗效评价， 记录结果。 结果： 治疗 10 次
后， A 组的有效率和显效率分别 为 1 7.46%和 4.76%， B 组分别 为 20.00%和 5.71%； 治疗 20 次后， A 组的有效率和显效率分别 为
46.03%和 23.81%， B 组分别为 65.71%和 42.86%。 两组治疗 10 次后的有效率和显效率比较差异均无统计学意义(P>0.05)， 治疗 20
次后的有效率和显效率均显著高于其治疗 10 次后(P<0.05)， B 组治疗 20 次后的有效率和显效率均显著高于 A 组(P<0.05)。 所有
患者的皮损均未出现严重不良反应。 结论： 308 nm 准分子光联合复方补骨脂酊外用 可提高内 蒙地区白 癜风患者颈、躯干、四肢的
非关节、非肢端及非骨隆起部位的白斑的疗效，且安全性较好。 |
| 英文摘要: |
| Objective:To compare the efficacy of 308 nm excimer lamp alone and 308 nm excimer lamp combined with
psoraleae tincture in the treatment of vitiligo in inner Mongolia.Methods:60 cases of patients with vitiligo in stationary phases were
enrolled (1 33 lesions were included), and randomly divided into 2 groups. The group A was treated with 308 nm excimer lamp alone,
while the group B was treated with 308 nm excimer lamp combined with psoraleae tincture. All the lesions were treated once a week,
topicas were used twice a day, all lesions were taken photos every ten times.Results:After ten times’ treatment, the effective rate and
significant rate of group A were 1 7.46% and 4.76% respectively, which were 20.00% and 5.71% in group B; after twenty times’
treatment, the effective rate and significant rate of group A were 46.03% and 23.81 %, which were 65.71 % and 42.86% in group B. There
was no significant difference between 2 groups in the effective rate and significant rate after ten times’ treatment (p>0.05), but the
effective rate and significant rate after twenty times’ treatment were obviously higher than those after ten times’ treatment (p<0.05), and
the effective rate and significant rate of group B were obviously higher than those of group A after twenty-times’ treatment (p<0.05). No
lesion experienced serious adverse reactions.Conclusion:308 nm Excimer Lamp combined with psoraleae tincture could significantly
improve the efficacy of lesions on neck, truck and limbs (non-articulus, non-outlimb and non-eminence of bone) of vitiligo in inner
Mongolia, and had good safety. |
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