| 王红 黄媛 王淼 郑纳新 林莉.肿瘤和非肿瘤患者合并肺栓塞的临床分析[J].现代生物医学进展英文版,2014,14(33):6527-6531. |
| 肿瘤和非肿瘤患者合并肺栓塞的临床分析 |
| Clinical Analysis of Tumor and Non-tumor Patients Complicated withPulmonary Embolism |
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| DOI： |
| 中文关键词: 恶性肿瘤 肺栓塞 D-二聚体 |
| 英文关键词: Malignant tumor Pulmonary embolism D-dimer |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨肿瘤和非肿瘤患者合并肺栓塞的临床特点及危险因素。方法：收集2009 年1 月至2013 年12 月我院收治的影像
学确诊肺栓塞患者78 例，按是否合并恶性肿瘤分为肿瘤组（n=42）和非肿瘤组（n=36），分析两组的临床特点、危险因素及实验室
指标。结果：肺癌是最容易发生肺栓塞的恶性肿瘤，腺癌是最常见的病理类型。肿瘤组肺栓塞50%发生在肿瘤确诊的3 个月内，肿
瘤组血清D-Dimer水平（3195.12± 4835.28滋g/L）高于非肿瘤组（1338.39± 1320.16滋g/L），两组间具有统计学差异（x2=2.172，P=0.03）。非
肿瘤组中冠心病、慢性肺病、糖尿病及高脂血症和脑梗塞与肿瘤组有显著性差异(P<0.01)。不明原因的呼吸困难50 例（64.10%）是
肺栓塞患者的主要症状，两组之间无明显差异；27 例（34.6%）患者合并下肢静脉血栓，右下肢静脉血栓高于左下肢，影像学肺栓塞
的类型以右肺动脉主干及其分支受累多见共39 例（50.0%），影像学表现在两组间无显著差异。结论：肿瘤组和非肿瘤组的临床症
状无明显差异，一旦确诊采取积极的抗凝溶栓治疗可以取得很好的疗效。 |
| 英文摘要: |
| Objective:To analyze the differences of the clinical characteristics and risk factors between tumor and non-tumor
complicated with pulmonary embolism.Methods:A retrospective analysis was conducted on 78 patients with pulmonary embolism who
were treated in our hospital fromJanuary 2009 to December 2013 and were divided into tumor group (n=42) and non-tumor group (n=36)
according to the pathological types of tumors. The relevant characteristics, the risk factors and the laboratory results were assessed and
compared between the two groups.Results:Lung cancer was prone to pulmonary embolism in malignant tumors and adenocarcinoma
was the commonest pathological type. 50% of pulmonary embolism in patients with tumor occurred within 3 months after tumor was
diagnosed. The level of serumD-dimer in tumor group was higher than that in non-tumor group (3195.12 ± 4835.28 滋g/L vs 1338.39 ±
1320.16 滋g/L), with a significant statistical difference (x2=2.172, P=0.03). Coronary heart disease, chronic lung disease, diabetes,
hyperlipemia and cerebral infarction were significantly different(P <0.01). Unexplained dyspnea (50/78, 64.10%) was the main symptom
of pulmonary embolismwithout significant difference (P>0.05). 27 patients (34.6%) were detected the deep venous thrombosis of lower
limb, and the right lower limb was more than the left. Right main pulmonary artery and its branches embolism were seen in 39 cases
(50%) without significant difference (P>0.05).Conclusion:There is no obvious or significant difference existed in clinical symptoms
between tumor and non-tumor patients complicated with pulmonary embolism. Using of anticoagulant and thrombolytic therapy can lead
to good curative effect upon diagnosis. |
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