| 徐蓉 黄婧娟 李瑞琳 荣棣君 郝长宁 石一沁 段俊丽.比较两种测量方法获得的血压波动对老年颈动脉斑块的影响[J].现代生物医学进展英文版,2014,14(33):6460-6463. |
| 比较两种测量方法获得的血压波动对老年颈动脉斑块的影响 |
| Effects of Blood Pressure Variability by Two Different Blood PressureFluctuation Assays on Carotid Atherosclerotic Plaque in the Elderly |
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| DOI： |
| 中文关键词: 血压波动 颈动脉斑块 老年男性 血压水平 |
| 英文关键词: Blood pressure fluctuations Carotid atherosclerotic plaque Elderly men Blood pressure |
| 基金项目:国家自然科学基金项目（11374213）；中国科学院红外物理国家重点实验实验室开放课题(200901) |
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| 中文摘要: |
| 目的：比较两种不同血压波动测定方法测定的血压波动与颈动脉斑块发生的关系。方法：以1456 名患有动脉硬化老年男性
患者为研究对象，监测患者24 h动态血压，根据有无颈动脉斑块将入选患者分为2 组：颈动脉斑块组（n=1012）和无颈动脉斑块组
（n=444），分别采用经典的标准差方法（SD 法）和个体血压波动测定方法（个体法）分别测定每位患者的血压波动，回顾性分析这
两种方法测定的血压波动与颈动脉斑块形成的关联性。结果：SD 法测定颈动脉斑块组24 h收缩期血压波动（SBPV）、白天
SBPV、夜间SBPV 以及24 h舒张期血压波动（DBPV）水平均明显高于无颈动脉斑块组（P<0.05）；而白天和夜间DBPV 差异无统
计学意义。个体法测定颈动脉斑块组24 h SBPV、白天SBPV、24 h DBPV以及白天DBPV 水平较无颈动脉斑块组均明显升高
（P<0.05）；夜间SBPV 和夜间DBPV 差异无统计学意义（P>0.05）。比较颈动脉斑块组SBPV 值出现次数，SD 法测定SBPV 最多的
是10-15 mmHg（n=541），其次是大于15 mmHg（n=399）；个体法测定颈动脉斑块组SBPV 值出现次数最多的是0-8 mmHg
（n=490），其次是8-10 mmHg（n=350）。结论：在老年男性动脉硬化相关疾病患者中，血压波动与颈动脉斑块的形成有着密切的关
系，两种方法均可测定血压波动，但以个体血压波动测定方法更加敏感。 |
| 英文摘要: |
| Objective:To compare the two different blood pressure measurement methods for the determination of the
relationship between carotid atherosclerotic plaque and fluctuations of blood pressure in elderly people.Methods:1456 cases of elderly
male patients suffering from arteriosclerosis were enrolled in the study. All patients underwent ambulatory blood pressure monitoring and
extracranial carotid ultrasound examination. Extracranial carotid artery plaque index (PI) was calculated, and patients were grouped as
carotid plaque group and control group of non-carotid plaque according to the results of PI. Classical standard deviation method (SD
method) and individual measurement of blood pressure fluctuations method (individual method) were used. The correlation of the blood
pressure fluctuations and carotid plaque formation of these two methods were retrospectively analyzed.Results:With SD method, the
levels of 24 h systolic blood pressure variability (SBPV), daytime SBPV, nighttime SBPV and 24 h diastolic blood pressure variability
(DBPV) of carotid artery plaque group were significantly higher than those of non-carotid plaque group (P <0.05); The differences of
daytime and nighttime DBPV had no statistical significance (P>0.05). With individual method, the levels of 24 h SBPV, daytime SBPV,
24 h DBPV and daytime DBPV of carotid artery plaque group were significantly higher than that of non-carotid plaques group (P <0.05).
There was no significant difference between night SBPV and night DBPV. Compared with the value of SBPV occurrence in carotid
artery plaque group, the most frequent appearance is 10-15mmHg range for the determination of SBPV by SD method (n = 541),
followed by more than 15 mmHg (n = 399); while the most frequent appearance is 0-8 mmHg by individual method (n = 490), followed
by more than 8-10 mmHg (n = 350).Conclusion:Both of the two methods indicate that the formation of the carotid atherosclerotic
plaques in elderly people is related significantly with the fluctuation of blood pressure, but it is more sensitive to measure by individual
method. |
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