| 韦宏 贾静 李光男 杨庆辉 陈延军.低剂量多巴胺对急性心衰合并肾功能不全患者的影响[J].现代生物医学进展英文版,2014,14(32):6300-6302. |
| 低剂量多巴胺对急性心衰合并肾功能不全患者的影响 |
| Effect of Low-Dose Dopamine on the Patients of Acute Heart Failurewith Renal Dysfunction |
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| DOI： |
| 中文关键词: 多巴胺 急性心力衰竭 肾功能不全 |
| 英文关键词: Dopamine Acute Heart Failure Renal Dysfunction |
| 基金项目:黑龙江省自然科学基金项目（D201101） |
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| 中文摘要: |
| 目的：探讨低剂量多巴胺能否通过利尿作用改善急性左心衰患者的充血症状以及肾功能。方法：将2013 年9 月至2013 年
12 月我院收治的80 例急性心衰合并肾功能不全的患者随机分为对照组和治疗组，每组各40 例。对照组给予常规治疗，治疗组在
常规治疗的基础上加用小剂量多巴胺静脉泵入48 小时。观察和比较两组患者48 小时内的总尿量及血清胱抑素C的变化、充血
症状、肾功能及临床疗效的差异。结果：与对照组相比，治疗组48 小时总尿量、血清胱抑素C 的变化、体重变化、BNP变化、肌酐变
化、进展性心衰发生率、死亡率、治疗失败患者比例均无明显差异(P＞0.05)。结论：低剂量多巴胺不能在利尿治疗基础上减轻急性
心力衰竭并发肾功能不全患者的充血症状或改善肾功能。 |
| 英文摘要: |
| Objective:To investigate the effect of low-dose dopamine on the decongestion symptoms and renal function of patients
with acute heart failure.Methods:80 patients with acute heart failure and renal dysfunction admitted in our hospital fromSeptember 2013
to December 2013 were randomized into the treatment group and control group. The control group accepted the conventional treatment,
while the treatment group was administered with the same treatment addition of low-dose dopamine. The 48-hour cumulative urine volume,
change of serum cystatin C levels, decongestion symptoms, renal function and clinical efficacy were observed and compared.Results:Compared with the control group, low-dose dopamine had no significant effect on the 48-hour cumulative urine volume, change of serum
cystatin C level, weight, BNP, creatinine, incidence rate of advanced heart failure, mortality and ratio of failed patients (P>0.05).Conclusion:Low-dose dopamine couldn't relieve the decongestion symptoms or improve the renal function of patients with acute heart failure
and acute renal insufficiency on the basis of diuretic treatment. |
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