| 杨鑫 祁全 陶学强 张文龙 王金龙.药物及靶向治疗在脊髓损伤中的治疗新进展[J].现代生物医学进展英文版,2014,14(31):6174-6176. |
| 药物及靶向治疗在脊髓损伤中的治疗新进展 |
| The Progress of Drugs and Target Therapy in the Treatmentof Spinal Cord Injury |
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| DOI： |
| 中文关键词: 脊髓损伤 药物治疗 靶向治疗 新进展 |
| 英文关键词: Spinal cord injury Drug treatment Targeted therapy The new progress |
| 基金项目:黑龙江省自然科学基金项目（D201262） |
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| 中文摘要: |
| 脊髓损伤(spinal cord injury, SCI)是一种严重的损伤，它对患者的影响是相当持久的，SCI治疗的难点主要是由于损伤后脊髓
中的微环境不利于神经细胞的再生、轴突的生长和新突触的形成，从而影响了脊髓组织的修复。现在SCI治疗的策略就是要改善
损伤脊髓微环境，减少不利因素，从而促进脊髓结构修复和功能重建。本研究综述近年来逐渐发展起来的药物及靶向治疗方法，
为SCI的新治疗提供参考依据，真正提高患者的生活质量。 |
| 英文摘要: |
| Spinal cord injuries (spinal cord injury, SCI) is a serious damage, and its impact on patients is quite durable. SCI
treatment is mainly due to the difficulty of microenvironment in the spinal cord after injury of nerve cells in the regeneration of axons, the
growth and the formation of new synapses, which affects the spinal cord tissue repair. Now SCI treatment strategy is to improve the
spinal cord injury microenvironment, and reduce adverse factors, so as to promote repair of spinal cord structure and functional
reconstruction. This study summarized the targeted drugs and therapies in order to provide a reference basis for new treatment for SCI,
and to really improve the quality of life. |
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