| 严华 徐广 胡正清 侯宏伟 胡华兵.坎地沙坦酯治疗老年患者原发性高血压的疗效及安全性分析[J].现代生物医学进展英文版,2014,14(31):6107-6109. |
| 坎地沙坦酯治疗老年患者原发性高血压的疗效及安全性分析 |
| Analysis of Efficacy and Safety of Candesartan Cilexetil in the Treatmentof Elderly Hypertensive |
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| DOI： |
| 中文关键词: 坎地沙坦酯 依那普利 原发性高血压 |
| 英文关键词: Candesartan cilexetil Enalapril Essential hypertension |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨坎地沙坦酯治疗老年高血压患者的疗效和安全性。方法：选取我院110例老年原发性高血压患者，随机分为观察
组（坎地沙坦酯治疗）和对照组(依那普利治疗)，对比分析两组患者药物治疗前、后的动态血压监测及相关指标。结果：经两个月治
疗后，两组患者坐位收缩压(SBP)及舒张压(DBP)谷值均较基线明显降低，观察组下降幅度明显大于对照组，差异有统计学意义
（P<0.05）；观察组的总有效率为90.91%，明显高于对照组的76.36%，差异有统计学意义（P<0.05）。结论：坎地沙坦酯治疗老年患者
原发性高血压疗效显著，可明显降低收缩压和舒张压，是治疗老年性高血压理想的制剂。 |
| 英文摘要: |
| Objective:To explore the efficacy and safety of candesartan cilexetil in the treatment of elderly hypertensive.Methods:110 cases of elderly patients with essential hypertension in our hospital were selected and randomly divided into the observation group (
treated with candesartan ) and the control group (treated with enalapril), ambulatory blood pressure were monitored and related indicators
in the two groups of patients were comparatively analyzed before and after treatment.Results:After two months of treatment, the sitting
systolic blood pressure ( SBP ) and diastolic blood pressure (DBP) of the two groups were significantly lower, but decreased significantly
in the observation group than in control group, the difference had statistical significance (P<0.05); The total effective rate of observation
group was 90.91%, significantly higher than that of the control group (76.36%), and the difference had statistical significance(P<0.05).Conclusion:Candesartan cilexetil has significantly curative effect in the treatment of elderly patients with essential hypertension, it can
significantly reduce the systolic and diastolic blood pressure, which is an ideal preparation in the treatment of elderly patients with
essential hypertension. |
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