| 彭旭 张智博 谭红 张丹 唐璐 肖乐 王爱民 梁永.序贯肠内营养对老年重症脑卒中患者营养代谢、免疫功能及预后的影响[J].现代生物医学进展英文版,2014,14(29):5683-5686. |
| 序贯肠内营养对老年重症脑卒中患者营养代谢、免疫功能及预后的影响 |
| Effect of Sequential Enteral Nutrition on Nutritional Metabolism, ImmuneFunction and Prognosis in Eldly Patients with Severe Stroke |
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| DOI： |
| 中文关键词: 序贯肠内营养 重症脑卒中 免疫功能 |
| 英文关键词: Sequential enteral nutrition Severe stroke Immune function |
| 基金项目:湖南省卫生厅科技计划项目（B2012-135） |
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| 中文摘要: |
| 目的：探讨序贯肠内营养对老年重症脑卒中患者营养代谢、免疫功能和预后的影响。方法：将90 例老年重症脑卒中患者随
机分为序贯肠内营养组30 例、肠内营养组30 例和对照组30 例予以营养支持。入院第1 天和第14 天分别检测患者营养指标、免
疫功能指标、格拉斯哥昏迷评分（GCS）、美国国立卫生院神经功能缺损评分（NIHSS）；统计3 组患者住院期间并发症发生率。结
果：治疗14 天后3 组各项指标均较第1 天明显下降，对照组较序贯肠内营养组和肠内营养组下降更明显；与对照组相比较，治疗
14 天后序贯肠内营养组和肠内营养组TLC、IgA，IgM，IgG 水平明显升高；GCS 评分明显升高，NIHSS评分明显降低；序贯肠内营
养组、肠内营养组各项并发症较对照组发生率低。结论：老年重症脑卒中患者随病程延长，营养状况呈恶化趋势。肠内营养可改善
患者营养状况，改善机体免疫功能，降低并发症发生率，改善预后。序贯肠内营养较肠内营养效果更佳。 |
| 英文摘要: |
| Objective:To investigate the effect of sequential enteral nutritional support on nutritional metabolism, immune
function and prognosis in elderly patients with severe stroke.Methods:Ninety elderly patients with severe stroke were selected and
randomly divided into three groups: SEN(sequential enteral nutrition) group, EN (enteral nutrition) group and the control group who were
given normal liquid diet. To count the complication rates, indicators related to nutrition and immune were tested, and Glasgow coma
score (GCS)and National Institutes of Health Stroke Scale (NIHSS) were also used at the 1st day and 14th day of hospitalization.Results:The nutritional index decreased at the 14th day after admission in all the three groups, and there was a more significant decrease in the
control group ( P < 0. 05). Compared with the control group, after 14-day nutrition support, the levels of the blood total lymphocyte count
(TLC), IgA, IgMand IgG in SEN group and EN group were obviously higher, and the GCS showed significant increase while the NIHSS
markedly decreased. And also the complication rate was lower in SEN group and EN group than that in control group.Conclusion:Since the nutritional conditions were deteriorated in elderly patients with severe stroke with the duration of stroke, enteral nutritional
support can improve nutritional status, enhance immune function, reduce the complication rates and improve clinical prognosis. And the
sequential enteral nutrition support was more effective than the enteral nutrition support. |
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