赵燕 王晓燕 刘丽平 王景玲 李玉梅.老年原发性高血压患者脉搏波传导速度与心脑血管危险因素关系的研究[J].现代生物医学进展英文版,2014,14(27):5290-5292. |
老年原发性高血压患者脉搏波传导速度与心脑血管危险因素关系的研究 |
The Correlation of Pulse Wave Velocity with CardiovascularRisk Factors in Patients with Essential Hypertension |
|
DOI: |
中文关键词: 原发性高血压 老年 心脑血管风险因素 肱踝脉搏波传导速度 |
英文关键词: Essential hypertension Elderly Cardiovascular risk factors BaPWV |
基金项目: |
|
Hits: 789 |
Download times: 929 |
中文摘要: |
目的:探讨老年原发性高血压患者脉搏波传导速度与心脑血管危险因素关系。方法:随机选取2012 年5月至2012 年8 月在
我院体检的160 例新诊老年原发性高血压患者及120 例健康个体,所有个体均未接受治疗,采用动脉硬化检测仪测定患者肱踝
脉搏波传导速度(baPWV),同时测量身高、腰围、体重、血压、总胆固醇(TC)、甘油三酯(TG)、空腹血糖(FBS)、低密度脂蛋白胆固醇
(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、尿酸(UA)、肌酐(Cr)等指标,探讨老年原发性高血压患者高脂血症、吸烟、肥胖、糖尿病等
危险因素与baPWV 指标变化的关系。结果:不同血压分级的老年原发性高血压患者之间肱踝脉搏波传导速度值存在显著差异
(P<0.01)。合并冠心病、肥胖、糖尿病、吸烟、高脂血症等危险因素的高血压患者baPWV值显著高于单纯性原发性高血压患者(P<0.01)。多
元回归分析表明:吸烟史(P<0.01)、冠心病史(P<0.01)、糖尿病史(P<0.01)、年龄(P<0.01)、腰围(P<0.01)、血压(P<0.01)、HDL-C(P<0.01)、
TC(P<0.01)、FBS(P<0.01)、LDL-C(P<0.01)、Cr(P<0.01)是baPWV 升高的独立风险因素。结论:老年原发性高血压患者存在不同程
度的的动脉僵硬增高,常见心脑血管风险因素同样影响老年原发性高血压患者僵硬度。 |
英文摘要: |
Objective:To investigate the association of pulse wave velocity and cardiovascular risk factors in elderly hypertensive
patients.Methods:From May 2012 to August 2012, 160 newly diagnosed elderly patients with essential hypertension were randomly
selected from cardiology outpatient department. Brachial-ankle pulse wave velocity (baPWV) were measured by arteriosclerosis
detection, simultaneous measurement of the height, waist circumference, body weight, blood pressure, total cholesterol (TC), triglyceride
(TG), fasting blood sugar (FBS), low-density lipoprotein cholesterol(LDL-C), high density lipoprotein lipoprotein cholesterol (HDL-C),
uric acid (UA), creatinine (Cr) and other indicators, to explore the relationship between changes with hyperlipidemia, smoking, obesity,
diabetes and other risk factors associated with baPWV indicators in elderly hypertensive patients.Results:Brachial-ankle pulse wave
velocity values were significantly different(P<0.01) between the different classification of blood pressure in elderly patients with essential
hypertension. Coronary heart disease, obesity, diabetes, smoking, hyperlipidemia and other risk factors in hypertensive patients with
baPWV value was significantly higher than the Simple patients with essential hypertension(P<0.01). Multiple regression analysis showed
that a history of smoking (P<0.01), history of coronary artery disease (P<0.01), history of diabetes (P<0.01), age (P<0.01), waist
circumference (P<0.01), blood pressure (P<0.01), HDL-C (P<0.01), TC (P<0.01), FBS (P<0.01), LDL-C (P<0.01), Cr (P<0.01) were
independent risk factors of increase of baPWV.Conclusion:The elderly hypertensive patients had different degrees of increased arterial
stiffness, common cardiovascular risk factors also affected the stiffness of elderly patients with essential hypertension. |
View Full Text
View/Add Comment Download reader |
Close |
|
|
|