| 李勇 毕涛 张炳远 冯玉杰 郝翠萍 赵伟.中国肝细胞癌患者TACE术后死亡原因分析[J].现代生物医学进展英文版,2014,14(26):5152-5157. |
| 中国肝细胞癌患者TACE术后死亡原因分析 |
| Complications of Transcatheter Hepatic Arterial Chemoembolization (TACE)in Chinese Hepatocellular Carcinoma Patients RunningTitle: TACE-associated Mortality in China |
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| DOI： |
| 中文关键词: 肝动脉化疗栓塞术 肝细胞癌 死亡原因 |
| 英文关键词: Transcatheter hepatic arterial chemoembolization Hepatocellular carcinoma Death Etiology |
| 基金项目: |
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| 中文摘要: |
| 目的：通过探讨中国肝细胞癌患者肝动脉化疗栓塞术（TACE）术后并发症及死亡原因，来提高临床治疗效果，并积累治疗经
验。方法：通过联合检索CBM及CNKI 上从1994 年1 月到2008 年9 月的关于中国肝细胞癌患者行TACE 术后出现并发症的
相关文章，分析总结肝细胞癌患者TACE 术后死亡的原因及特点。结果：中国肝细胞癌患者TACE 术后并发症较为危重，致死率
较高，死亡原因有84%是肝功能衰竭、上消化道出血及肝癌破裂出血，且死亡病例发生在术后1 月内的占78.7%，因此大多是早期
死亡。结论：中国肝细胞患者TACE 术后死亡原因主要是肝功能衰竭、上消化道出血及肝癌破裂出血，且术后死亡常为早期死
亡，因此TACE 术后严重并发症可直接影响患者的预后情况，我们需要提高对TACE术选择时机的重视程度，规范介入治疗手段
和流程，尽量避免和减少严重并发症的发生。 |
| 英文摘要: |
| Objective:To discuss the complications related to TACE in Chinese patients so as to increase the clinical effect and to
gain more experience.Methods:We retrieved articles fromJanuary 1994 to September 2008 in Chinese Medical Current Content (CBM)
and National Knowledge Infrastructure (CNKI). Meta-analysis was performed on the results of homogeneous studies. All calculations for
the current meta-analysis were performed using REVIEWMANAGER 4.2.Results:There were 150 reported cases of deaths after TACE,
among which hepatic failure, upper gastrointestinal bleeding and ruptured liver cancer with hemorrhage occurred in 84% of cases, and
78.7% survived less than one month after operation.Conclusion:The primary etiology of death following TACE is acute liver failure,
upper gastrointestinal bleeding and ruptured liver cancer with hemorrhage. The majority of peri-procedure fatalities are less than 30 days
following TACE. |
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