| 何芳 黄志军 周玉庆 李长罗 宋坤.长沙市PM10 与脑卒中急诊关系的病例交叉研究[J].现代生物医学进展英文版,2014,14(24):4695-4697. |
| 长沙市PM10 与脑卒中急诊关系的病例交叉研究 |
| A Case-Crossover Study on PM10 and Emergency Hospital Visitsfor Stroke in Changsha |
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| DOI： |
| 中文关键词: 脑卒中 急诊 可吸入颗粒物 病例交叉研究 |
| 英文关键词: Stroke Emergency hospital visit PM10 Case-crossover study |
| 基金项目:国家自然科学基金项目（81202166）；中南大学中央高校基本科研业务费专项资金（2012QNZT166）；
湖南省社会发展支撑计划一般项目（2011FJ4266） |
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| 中文摘要: |
| 目的：探讨长沙市大气可吸入颗粒物(PM10)与脑卒中急诊的相关性。方法：收集2008-2009 年间长沙市每日脑出血和脑梗死急诊数据，同期收集长沙市大气可吸入颗粒物(PM10)及相关气象数据，利用季节分层的单向回顾性1:1 配对病例交叉研究设计，建立单污染物模型和多污染物模型进行分析。结果：在调整气温和相对湿度的单污染物滞后模型中，秋季滞后0、1、2 天的PM10日均浓度每增加10 ug/m3，与脑出血和脑梗死的的OR (95%CI) 值分别为0.953 (0.871-1.042) 和0.970(0.910-1.034)、0.984(0.913-1.061)和0.965(0.902-1.031)、0.996(0.928-1.069)和0.964(0.904-1.029)，关联具有统计学意义（P<0.05）。结论：长沙市PM10 浓
度变化对脑卒中发病有影响。 |
| 英文摘要: |
| Objective:To investigate the correlation between particulate matters with an aerodynamic diameter of <10 um (PM10)
and emergency hospital visits（EHVs）for stroke in Changsha.Methods:The daily EHVs for stroke were gathered from Changsha central
hospital and the third Xiangya hospital during 2008-2009. The corresponding air pollutions, meteorological data were collected. The
seasonal-stratified case-crossover design with 1:1 matched pair was used to set up single-pollution models for the data analysis.Results:After adjusting the temperature and relative humidity in single-pollution models, an increase of 10 ug/m3 increase in PM10 were
significantly association with EHVs of cerebral hemorrhage and cerebral infarction at lags of 0 day [OR=0.953 (95%CI: 0.871-1.042) and
OR=0.970 (95%:0.910-1.034, separately)], 1day [OR=0.984 (95%CI: 0.913-1.061) and OR=0.965 (95%:0.902-1.031, separately)] and 2
day [OR=0.996 (95%CI: 0.928-1.069) and OR=0.964 (95%:0.904-1.029, separately)]in autumn.Conclusion:Elevated the concentration
of PM10 was associated with increased EHVs for stroke in Changsha. |
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